2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-106175
    Detiviciclovir 220984-26-9 98%
    Detiviciclovir (AM365) is an antiviral nucleoside analogue.
    Detiviciclovir
  • HY-106188
    L 756423 216863-66-0 98%
    L 756423 is a potent HIV protease inhibitor. L 756423 has the potential for the research of HIV infection.
    L 756423
  • HY-106205
    Di-Val-L-dC 380886-96-4 98%
    Di-Val-L-dC, a prodrug of L-deoxycytidine, is a selective and specific anti-HBV agent.
    Di-Val-L-dC
  • HY-106216
    Tiprelestat 820211-82-3 98%
    Tiprelestat is a potent human neutrophil elastase inhibitor. Tiprelestat has antimicrobial and anti-inflammatory activities. Tiprelestat can be used in the research of inflammation/immune disease.
    Tiprelestat
  • HY-106235
    LB80317 441785-24-6 98%
    LB80317 is an active metabolite of LB80380 and suppresses the DNA synthesis of HBV with an EC50 of 0.5 μM. LB80317 has antiviral effect and has the potential for chronic hepatitis B treatment.
    LB80317
  • HY-106252
    KP-1212 114522-16-6 98%
    KP-1212 is a nucleoside. KP-1212 exerts its antiviral effect by mutagenizing the viral genome. KP-1212 inhibits HIV growth.
    KP-1212
  • HY-106270
    KP-1461 815588-85-3 98%
    KP-1461, nucleoside derivative, is an anti-HIV agent. KP-1461 can induce lethal mutations in viruses. KP-1461 can be used for the research of HIV infection.
    KP-1461
  • HY-106276
    (D-Ala)-Peptide T 106362-33-8 98%
    (D-Ala)-Peptide T is an octapeptide derived from gp120. (D-Ala)-Peptide T releases chemokines and prevents HIV-1 GP120-induced neuronal death. (D-Ala)-Peptide T can be used in research on infectious and neurological diseases such as AIDS-related dementia.
    (D-Ala)-Peptide T
  • HY-106338
    Polyketomycin 200625-47-4 98%
    Polyketomycin is a tetracyclic quinone glycoside antibiotic isolated from Streptomyces sp. or Streptomyces diastatochromogenes. Polyketomycin inhibits growth of Gram-positive bacteria, and its MIC values is less than 0.2 µg/mL. Polyketomycin has antibacterial, anticancer, antimalarial activities.
    Polyketomycin
  • HY-106359
    Delmitide 287096-87-1 98%
    Delmitide (RDP58) is an orally active d-isomer decapeptide with potent anti-inflammatory activity. Delmitide inhibits production of TNF-α, IFN-γ, and interleukin (IL)-12, and up-regulates heme oxygenase 1 activity. Delmitide can be used for the research of ulcerative colitis.
    Delmitide
  • HY-106371
    Siccanin 22733-60-4 98%
    Siccanin is a succinate dehydrogenase (SDH) inhibitor (IC50=0.9 μM) with species-selective activity. Siccanin also is a antibiotic against pathogenic fungi.
    Siccanin
  • HY-106422
    EDP-420 736992-12-4 98%
    EDP-420 (EP-013420; S-013420) is an orally active antibacterial agent. EDP-420 inhibits the Mycobacterium avium complex (MAC) in macrophages. EDP-420 reduces bacterial counts in a mouse model of macrolide infection. EDP-420 inhibits pneumococcal activity in a rabbit model of meningitis. EDP-420 can be used in research on inflammatory infectious diseases such as meningitis.
    EDP-420
  • HY-106476
    Primidolol 67227-55-8 98%
    Primidolol (UK-11443), derived from Parmotrema perlatum, possesses antibacterial and antioxidant activities. Primidolol is also an orally active α/β Adrenergic Receptor blocker with antihypertensive activity. Primidolol can be used in research related to infections and cardiovascular diseases.
    Primidolol
  • HY-106492
    Amocarzine 36590-19-9 98%
    Amocarzine (CGP 6140) is an orally active antifilarial agent. Amocarzine can result in the swelling of mitochondrion and inhibit respiration and other associated metabolic functions. Amocarzine can be used for the research of infection.
    Amocarzine
  • HY-106526
    Xibornol 13741-18-9 98%
    Xibornol (Bactacine) has strong antibacterial action against Streptococcus pneumoniae, Streptococcus pyogenes, and Staphyloccus aureus, as well as against Actinomyces israelii and Corynebacterium ulcerans. Xibornol has the potential for using for the antisepsis of the oral cavity and as adjuvant in pharyngeal infections caused by Gram-positive microorganisms.
    Xibornol
  • HY-106542
    Eberconazole 128326-82-9 98%
    Eberconazole is a dichlorinated imidazole derivative with antifungal activity. Eberconazole is more effective than Clotrimazole (HY-10882), Ketoconazole (HY-B0105), and Miconazole (HY-B0454). Eberconazole has potential for the study of dermatophytosis.
    Eberconazole
  • HY-106574
    Ceftobiprole medocaril 376653-43-9 98%
    Ceftobiprole medocaril (BAL5788) is the parenteral proagent of Ceftobiprole (HY-112579). Ceftobiprole is a parenteral pyrrolidinone cephalosporin. Ceftobiprole is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci. Ceftobiprole also inhibits gram-positive and gram-negative pathogens.
    Ceftobiprole medocaril
  • HY-106585
    Cyclobendazole 31431-43-3 98%
    Cyclobendazole is a benzimidazole derivative against protozoan parasites. Cyclobendazole shows in vitro activities against Trichomonas vaginalis (30236) and Giardia lamblia (wt), with IC50 values of 1.1 and 0.047 μg/mL, respectively.
    Cyclobendazole
  • HY-106597
    Pirlimycin 79548-73-5 98%
    Pirlimycin, a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome.
    Pirlimycin
  • HY-106668
    Isepamicin 58152-03-7 98%
    Isepamicin (Sch 21420) is an aminoglycoside antibacterial. Isepamicin has better activity against strains producing type I 6'-acetyltransferase. Isepamicin’s antibacterial spectrum includes Enterobacteriaceae and staphylococci. Anaerobes, Neisseriaceae and streptococci are resistant. Isepamicin exhibits a strong concentration-dependent bactericidal effect, a long post-antibiotic effect (several hours) and induces adaptive resistance.
    Isepamicin
Cat. No. Product Name / Synonyms Application Reactivity