2. Anti-infection
  3. Antibiotic Bacterial
  4. Isepamicin

Isepamicin (Sch 21420) is an aminoglycoside antibacterial. Isepamicin has better activity against strains producing type I 6'-acetyltransferase. Isepamicin’s antibacterial spectrum includes Enterobacteriaceae and staphylococci. Anaerobes, Neisseriaceae and streptococci are resistant. Isepamicin exhibits a strong concentration-dependent bactericidal effect, a long post-antibiotic effect (several hours) and induces adaptive resistance.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Isepamicin sulfate) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Isepamicin Chemical Structure

Isepamicin Chemical Structure

CAS No. : 58152-03-7

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Isepamicin Related Antibodies

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Description

Isepamicin (Sch 21420) is an aminoglycoside antibacterial. Isepamicin has better activity against strains producing type I 6'-acetyltransferase. Isepamicin’s antibacterial spectrum includes Enterobacteriaceae and staphylococci. Anaerobes, Neisseriaceae and streptococci are resistant. Isepamicin exhibits a strong concentration-dependent bactericidal effect, a long post-antibiotic effect (several hours) and induces adaptive resistance[1].

IC50 & Target

Aminoglycoside

 

Molecular Weight

569.60

Formula

C22H43N5O12
CAS No.
SMILES

NC[C@H](O)C(N[C@H](C[C@@H]([C@H]([C@@H]1O)O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CN)N)[C@@H]1O[C@@H]3[C@@H]([C@H]([C@@](O)(CO3)C)NC)O)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Isepamicin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isepamicin58152-03-7Sch 21420Sch21420Sch-21420AntibioticBacterialaminoglycoside antibacterialtype I 6'-acetyltransferaseadaptive resistanceInhibitorinhibitorinhibit

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