2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-119583
    Furanomycin 18455-25-9 98%
    Furanomycin can resist Gram-positive and negative bacteria and inhibit the bacteriophage of Escherichia coli. Furanomycin is also a L-isoleucine competitive antagonist.
    Furanomycin
  • HY-119604
    Cafamycin 112303-17-0 98%
    Cafamycin is a polyether antibiotic active against gram-positive bacteria, including Staphylococcus aureus. Cafamycin also demonstrates insecticidal and antiprotozoal activities. Cafamycin is isolated from the culture fluid of Streptomyces sp., an organism producing the anthracycline antibiotic galtamycin.
    Cafamycin
  • HY-119609
    Ilicicolin C 22562-67-0 98%
    Ilicicolin C exhibits antibacterial activity against Pseudomonas syringae with IC50 of 28.5 µg/mL. Ilicicolin C exhibits weak inhibitory activities against acetylcholinesterase (AChE) and β-glucuronidase with IC50 of 30-43 µg/mL. Ilicicolin C exhibits weak cytoxicity in human lung fibroblasts with IC50 of 64-120 µg/mL. Ilicicolin C affects seed germination and root tip growth of lettuce.
    Ilicicolin C
  • HY-119674
    Xanthopterin 119-44-8 98.0%
    Xanthopterin, an unconjugated pteridine compound, is the main component of the yellow granule in the Oriental hornet bear wings, produces a characteristic excitation/emission maximum at 386/456 nm. Xanthopterin (XPT) causes renal growth and hypertrophy in rat. Xanthopterin inhibits RNA synthesis.
    Xanthopterin
  • HY-119686
    Miloxacin 37065-29-5 98%
    Miloxacin is an orally active bacteriostatic agent targeting Gram-negative bacteria, exhibiting antibacterial properties similar to Oxolinic acid (HY-B1002) and Nalidixic acid (HY-B0398).
    Miloxacin
  • HY-119690
    T326 1451042-19-5 98%
    T326 is a potent and selective HDAC3 inhibitor, with an IC50 of 0.26 μM. T326 can be used for the research of cancer and HIV infection.
    T326
  • HY-119728
    FR198248 197316-54-4 98%
    FR198248 is an anti-influenza agent and peptide deformylase (PDF) inhibitor. FR198248 can be isolated from Aspergillus flavipes. FR198248 potently inhibits the PDF of Staphylococcus aureus with an IC50 of 3.6 µM. FR198248 can be used for antiviral and antibacterial research.
    FR198248
  • HY-119789
    Albofungin 37895-35-5 98%
    Albofungin (Antibiotic P-42-1) is isolated from the culture filtrate of Actinomyces tumemacerans strain INMI.P-42. Albofungin shows highly active on a wide variety of gram-positive bacteria and fungi. Albofungin shows cytotoxic to HeLa cell cultures and exhibited antitumor activity on EHRLICH ascites tumor in mice.
    Albofungin
  • HY-119815
    Tenonitrozole 3810-35-3 99.00%
    Tenonitrozole exhibits antibacterial activity through inhibition of pyruvate-ferredoxin oxidoreductase (PFOR). Tenonitrozole inhibits H. pylori and C. jejuni with MICs of 0.7 μM and 5.9 μM.
    Tenonitrozole
  • HY-119843
    Asterric Acid 577-64-0 98%
    Asterric acid is an antibiotic fungal metabolite that completely inhibits the binding of the potent vasoconstrictor endothelin (ET)-1 to the ETA receptor in A10 cells at 0.1 μM.1 Asterric acid derivatives have also been shown to inhibit VEGF-induced tube formation of human umbilical vein endothelial cells at 3-10 μM, which suggests its usefulness as an antiangiogenic agent.
    Asterric Acid
  • HY-119862
    Bupicomide 22632-06-0 98%
    Bupicomide is an inhibitor of dopamine beta-monooxygenase via fusaric acid. Bupicomide can be used in the research of hypertension.
    Bupicomide
  • HY-119893
    Diamfenetide 36141-82-9 99.72%
    Diamfenetide is used for the study of Fasciola hepatica infections in vitro. Diamfenetide leads to irreversible paralysis in vitro of immature and adult Fasciola hepatica.
    Diamfenetide
  • HY-119894
    Althiomycin 12656-40-5 98%
    Althiomycin is a polyketide synthase-derived thiazole antibiotic originally isolated from S. althioticus. It is active against Gram-positive bacteria, including S. aureus, S. epidermidis, and S. pyogenes (MICs=25, 25, and 3.1 μg/mL, respectively).2 Althiomycin inhibits protein synthesis in E. coli when used at concentrations of 1 and 10 μg/mL but not in isolated rabbit reticulocytes at 100 μg/mL.
    Althiomycin
  • HY-119900
    Carnidazole 42116-76-7 99.81%
    Carnidazole is an antiprotozoal agent of the nitroimidazole class. Carnidazole is used for the research of Trichomonas infection.
    Carnidazole
  • HY-119901
    Eupatarone 17249-61-5 98%
    Eupatarone (Caleprunin B) is a bacterial inhibitor. Eupatarone can be obtained from Calea platylepis.
    Eupatarone
  • HY-119929
    B 669 78182-92-0 98%
    B 669, a c10fazimine analogue, is an antimicrobial agent. B 669 has the activity against Mycobacterium ieprae.
    B 669
  • HY-119945
    Brobactam 26631-90-3 98%
    Brobactam is a potent synthetic wide spectrum β-lactamase inhibitor. Brobactam has antibacterial activity.
    Brobactam
  • HY-120004
    PF-06827443 2115022-67-6 98%
    PF-06827443 is a potent, low-clearance, orally bioavailable, and CNS-penetrant M1-selective positive allosteric modulator (PAM) with minimal agonist activity. PF-06827443 induce cholinergic AEs and convulsion.
    PF-06827443
  • HY-120104
    Nitidanin 171674-89-8 98%
    Nitidanin ((±)-Nitidanin) is an antimalarial and antiviral compound that can be isolated from the wood of Xanthoxylum nitidun D. C. Nitidanin is shows IC50 values of 21.2 and 18.4 μM for D6 and W2 clones of Plasmodium falciparum, respectively. Nitidanin can be used for the research of malaria and virus infection.
    Nitidanin
  • HY-120132
    KNI-102 139694-65-8 98%
    KNI-102 is a potent anti-HIV agent with an IC50 value of 100 nM for HIV protease.
    KNI-102
Cat. No. Product Name / Synonyms Application Reactivity