FR198248

Cat. No.: HY-119728: FAQs
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FR198248 is an anti-influenza agent and peptide deformylase (PDF) inhibitor. FR198248 can be isolated from Aspergillus flavipes. FR198248 potently inhibits the PDF of Staphylococcus aureus with an IC₅₀ of 3.6 µM. FR198248 can be used for antiviral and antibacterial research.

For research use only. We do not sell to patients.

FR198248 Chemical Structure

CAS No. : 197316-54-4

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Description	FR198248 is an anti-influenza agent and peptide deformylase (PDF) inhibitor. FR198248 can be isolated from Aspergillus flavipes. FR198248 potently inhibits the PDF of Staphylococcus aureus with an IC₅₀ of 3.6 µM. FR198248 can be used for antiviral and antibacterial research^[1]^[2].
IC₅₀ & Target	Influenza Virus, PDF^[1]^[2].
Molecular Weight	198.17
Formula	C₉H₁₀O₅
CAS No.	197316-54-4
SMILES	OC1OCC2=C1C(O)=C(O)C(O)=C2C
Structure Classification	Phenols Polyphenols
Initial Source	Microorganisms Aspergillus terreus
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (272 KB) Handling Instructions (2659 KB)
References	[1]. Nishihara Y, et al. FR198248, a new anti-influenza agent isolated from Aspergillus terreus No. 13830 I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities. The journal of antibiotics, 2001, 54(2): 136-143. [2]. Kwon YJ, et al. Isolation and identification of FR198248, a hydroxylated 1,3-dihydroisobenzofuran, from Aspergillus flavipes as an inhibitor of peptide deformylase. Biosci Biotechnol Biochem. 2010;74(2):390-3. [Content Brief]

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FR198248197316-54-4FR 198248FR-198248Influenza VirusS. aureusMRSAA. flavipesvirusbacterialinfectionInhibitorinhibitorinhibit

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FR198248

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