197316-54-4
197316-54-4
Chemical Structure
FR198248
- No. CAS: 197316-54-4
- Formula:C9H10O5
- Molecular Weight:198.17
IUPAC Name: 4-methyl-1,3-dihydroisobenzofuran-1,5,6,7-tetraol
InChIKey: GSKYCPXSDLXGEW-UHFFFAOYSA-N
SMILES: OC1OCC2=C1C(O)=C(O)C(O)=C2C
Biological Activity: FR198248 is an anti-influenza agent and peptide deformylase (PDF) inhibitor. FR198248 can be isolated from Aspergillus flavipes. FR198248 potently inhibits the PDF of Staphylococcus aureus with an IC50 of 3.6 µM. FR198248 can be used for antiviral and antibacterial research[1][2].
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FR198248 | FR198248 is an anti-influenza agent and peptide deformylase (PDF) inhibitor. FR198248 can be isolated from Aspergillus flavipes. FR198248 potently inhibits the PDF of Staphylococcus aureus with an IC50 of 3.6 µM. FR198248 can be used for antiviral and antibacterial research. | |||||||||||||||||||||
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References
- [1]. Nishihara Y, et al. FR198248, a new anti-influenza agent isolated from Aspergillus terreus No. 13830 I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities. The journal of antibiotics, 2001, 54(2): 136-143.
- [2]. Kwon YJ, et al. Isolation and identification of FR198248, a hydroxylated 1,3-dihydroisobenzofuran, from Aspergillus flavipes as an inhibitor of peptide deformylase. Biosci Biotechnol Biochem. 2010;74(2):390-3. [Content Brief]
Keywords
