Asterric Acid
Asterric acid is an antibiotic fungal metabolite that completely inhibits the binding of the potent vasoconstrictor endothelin (ET)-1 to the ETA receptor in A10 cells at 0.1 μM.1 Asterric acid derivatives have also been shown to inhibit VEGF-induced tube formation of human umbilical vein endothelial cells at 3-10 μM, which suggests its usefulness as an antiangiogenic agent.
For research use only. We do not sell to patients.
- CAS No.: 577-64-0
- Formula: C17H16O8
- Molecular Weight:348.30
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Antibiotic Isoforms
More
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A10 | IC50 |
1 x 10-5 M
Compound: 3
|
Displacement of endothelin-1 from ETA receptor in rat A10 cells
Displacement of endothelin-1 from ETA receptor in rat A10 cells
|
[PMID: 11809055] |
Chemical Information
-
CAS No. 577-64-0
-
Molecular Weight 348.30
-
Formula C17H16O8
-
SMILES
CC1=CC(O)=C(C(OC2=C(C=C(C=C2C(OC)=O)O)OC)=C1)C(O)=O
-
Synonyms
Dimethylosoic acid; RES-1214-1; TAN 1415A
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Asterric Acid Related Classifications
HY-119843 Related Classifications
Powered by Bioz