2. Infection

Infection (感染症)

Infection

関連製品

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

製品番号 製品名 CAS 番号 純度 構造式
  • HY-123315
    Sulfaperin 599-88-2 99.87%
    Sulfaperin (Methylsulfadiazin) is an antibacterial agent.
    Sulfaperin
  • HY-123319
    Antofloxacin hydrochloride 873888-67-6 98%
    Antofloxacin hydrochloride is a well tolerate, orally active and broad-spectrum 8-amino-fluoroquinolone with potent antibacterial activities. Antofloxacin hydrochloride shows superior antibacterial activity against gyrA mutation-positive H. pylori strains, especially in Asn87- mutated strains, compared to levofloxacin. Antofloxacin hydrochloride is a weak, reversible inhibitor of CYP1A2 for the research of infections caused by a diverse group of bacterial species.
    Antofloxacin hydrochloride
  • HY-123347
    TPU-0037C 485815-61-0 98%
    TPU-0037C is a metabolite of the marine actinomycete S. platensis that is structurally similar to Lydicamycin (HY-125414). It is active against Gram-positive bacteria (MICs=0.39-3.13 μg/mL), including methicillin-resistant S. aureus strains (MIC=3.13 μg/mL), but is ineffective against Gram-negative bacteria (MICs=>50 μg/mL).
    TPU-0037C
  • HY-123415
    PD 134922 150351-30-7 98%
    PD 134922 is a potent renin and HIV-1 protease inhibitor with an IC50 of 15 nM against HIV-1 protease.
    PD 134922
  • HY-123429
    CK0683A 83539-21-3 98%
    CK0683A is a novel biaminourea antibiotic with antiplaque effects and demonstrated efficacy in experimental mouse dental disease models. A 12-week study in beagles compared its efficacy in terms of plaque and gingivitis reduction, staining potential, and safety. Dogs were selected as the study subjects because the onset and progression of canine periodontal disease is similar to that of humans. As a positive control for plaque and gingivitis reduction and staining, chlorhexidine acetate was selected because it is effective in both humans and dogs.
    CK0683A
  • HY-123454
    SKF1 678997-25-6 98%
    SKF1 is a FK506 suppressor, causes a mitochondrially induced death in low salt, concomitant with the release of reactive oxygen species (ROS).
    SKF1
  • HY-123457
    PF-1163A 258871-59-9 98%
    PF-1163A is an antifungal agent that inhibits Ergosterol (HY-N0181) synthesis (IC50 = 12 ng/mL), which is found in a fermentation broth of Penicillium sp. PF-1163A also inhibits C-4 sterol methyl oxidase with an MIC value of 12.5 µg/mL.
    PF-1163A
  • HY-123479
    CK0492B 64169-11-5 98%
    CK0492B is a novel biaminourea antibiotic that has antiplaque properties in vitro and has shown efficacy in an experimental mouse dental disease model. A 12-week study in beagles compared its efficacy in reducing plaque and gingivitis, staining potential, and safety. Dogs were selected as the study subjects because the onset and progression of canine periodontal disease are similar to humans. Chlorhexidine acetate was selected as a positive control for plaque and gingivitis reduction and staining because it is effective in both humans and dogs.
    CK0492B
  • HY-123515
    Clorobiocin 39868-96-7 98%
    Clorobiocin is an antibacterial agent with an IC50 of 0.21 μM against the B subunit of E. coli DNA gyrase. Clorobiocin targets the mLaC protein of Gram-negative bacteria. Clorobiocin potently inhibits bacterial DNA replication. Clorobiocin can be used in studies on Gram-negative bacterial infections, such as Acinetobacter baumannii and E. coli infections.
    Clorobiocin
  • HY-123519
    14α-Hydroxy Paspalinine 151341-77-4 98%
    14α-Hydroxy Paspalinine is a paspalinine derivative with antiinsectan activity from the sclerotia of Aspergillus nomius.
    14α-Hydroxy Paspalinine
  • HY-123565
    TP-S1-68 120187-04-4 98%
    TP-S1-68 (Compound 10) is a TIE-2 inhibitor with an IC50 of 3.65 μM. TP-S1-68 exhibits antibacterial activity against a variety of fungal and bacteria. TP-S1-68 serves as a starting compound for the further development of TIE-2 inhibitors. TP-S1-68 can be used in research related to solid tumors, bacterial infections and fungal infections.
    TP-S1-68
  • HY-123598
    Corynecin III 18048-95-8 98%
    Corynecin III is a Chloramphenicol (HY-B0239)-like antibiotic, which is found in Corynebacterium. Corynecin III inhibits the growth of Gram-positive and Gram-negative bacteria with MIC values of 2.6-83 μg/mL.
    Corynecin III
  • HY-123608
    JE-2178 210181-19-4 98%
    JE-2178 is an orally available HIV-1 protease inhibitor with IC50 and Ki values are 15 and 0.318 nM respectively. JE-2178 has antiviral activity.
    JE-2178
  • HY-123614
    PD 140248 hydrochloride 147208-55-7 98%
    PD 140248 hydrochloride is a quinolone broad-spectrum antibacterial agent with good in vitro bacteriostatic activity, especially having a significant inhibitory effect on Gram-positive bacteria.
    PD 140248 hydrochloride
  • HY-123652
    Etofamide 25287-60-9 98%
    Etofamide is an antimicrobial agent with IC50 value of 5.96 mg/L against amoeba.
    Etofamide
  • HY-123686
    Ivermectin B1a monosaccharide 71837-27-9 98%
    Ivermectin B1a monosaccharide is a modified Ivermectin B1a (HY-126937). Ivermectin B1a monosaccharide is an antiparasite agent with a minimum concentration for full activity in Haemonchus contortus larval development of 0.001 μg/mL.
    Ivermectin B1a monosaccharide
  • HY-123711
    PC170942 867207-49-6 98%
    PC170942, a PC58538 analogue, is a potent FtsZ protein inhibitor. PC170942 is a cell division inhibitor, and shows antibacterial activities.
    PC170942
  • HY-123767
    HEC72702 1793063-59-8 98%
    HEC72702 is a potent and orally active hepatitis B virus capsid inhibitor with an EC50 values of 0.039 µM. HEC72702 dose-dependently reduced HBV DNA in both the plasma and livers.
    HEC72702
  • HY-123808
    MK-8325 1334312-52-5 98%
    MK-8325 (Compound 1) is an orally active HCV NS5A inhibitor. MK-8325 exhibits minimal inhibitory activity against hERG at a concentration of 30 mM. MK-8325 may be used in hepatitis C research.
    MK-8325
  • HY-123887
    Manumycin B 139023-58-8 98%
    Manumycin B is an antibiobic, and exhibits antitumor activity. Manumycin B is an inhibitor for acetylcholinesterase (AChE) with an IC50 of 15 mM.
    Manumycin B
製品番号 製品名 / Synonyms Application Reactivity