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Cat. No.: HY-123887

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Manumycin B

Manumycin B is an antibiobic, and exhibits antitumor activity. Manumycin B is an inhibitor for acetylcholinesterase (AChE) with an IC₅₀ of 15 mM.

For research use only. We do not sell to patients.

CAS No.: 139023-58-8
Formula: C₂₈H₃₄N₂O₇
Molecular Weight:510.58

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Manumycin B Chemical Structure

CAS No.: 139023-58-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Manumycin B is an antibiobic, and exhibits antitumor activity. Manumycin B is an inhibitor for acetylcholinesterase (AChE) with an IC₅₀ of 15 mM^[1]^[2].

IC₅₀ & Target

AChE

15 mM (IC₅₀)

All Antibiotic Isoforms :

All Cholinesterase (ChE) Isoforms :

AChE
BChE

Chemical Information

CAS No. 139023-58-8
Molecular Weight 510.58
Formula C₂₈H₃₄N₂O₇
SMILES

CCCC[C@@H](C)/C=C(C)/C(NC1=C[C@](/C=C/C=C/C=C/C(NC2=C(O)CCC2=O)=O)(O)[C@]3([H])O[C@]3([H])C1=O)=O
Structure Classification
- Antibiotics
- Other Antibiotics
Initial Source
- Microorganisms
streptomyces
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zheng ZH, et al., Isolation and characterization of N98-1272 A, B and C, selective acetylcholinesterase inhibitors from metabolites of an actinomycete strain. J Enzyme Inhib Med Chem. 2007 Feb;22(1):43-9. [Content Brief]

[2]. Grové J J C, et al., The first total synthesis of a type II manumycin antibiotic,(+)-TMC-1 A: the total syntheses of (–)-LL-C10037β and (+)-manumycin B[J]. Chemical Communications, 1999 (5): 421-422.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Manumycin B

All Antibiotic Isoforms

All Cholinesterase (ChE) Isoforms