PF-1163A
PF-1163A is an antifungal agent that inhibits Ergosterol (HY-N0181) synthesis (IC50 = 12 ng/mL), which is found in a fermentation broth of Penicillium sp. PF-1163A also inhibits C-4 sterol methyl oxidase with an MIC value of 12.5 µg/mL.
For research use only. We do not sell to patients.
- CAS No.: 258871-59-9
- Formula: C27H43NO6
- Molecular Weight:477.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 258871-59-9
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Molecular Weight 477.63
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Formula C27H43NO6
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SMILES
O=C(O[C@@H](CC[C@@H](CCCCC(N1C)=O)C)C[C@@H](O)CCC)[C@@H]1CC2=CC=C(C=C2)OCCO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Nose H, et al. PF1163A, a novel antifungal agent, inhibit ergosterol biosynthesis at C-4 sterol methyl oxidase. J Antibiot (Tokyo). 2002 Nov;55(11):969-74. [Content Brief]
[2]. Okabe M, et al. Macrolides from a Marine-Derived Fungus, Penicillium meleagrinum var. viridiflavum, Showing Synergistic Effects with Fluconazole against Azole-Resistant Candida albicans. J Nat Prod. 2016 Apr 22;79(4):1208-12. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PF-1163A Related Classifications
HY-123457 Related Classifications
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