2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-126787
    17-Hydroxyventuricidin A 113204-43-6 98%
    17-Hydroxyventuricidin A (YP-02259L-C) is an antimicrobial compound.17-Hydroxyventuricidin A inhibits the growth of the two tested filamentous fungi (Verticillium dahlia and Fusarium sp.) and of Candida tropicalis R2 CIP203.
    17-Hydroxyventuricidin A
  • HY-126795
    Aspergillin PZ 483305-08-4 98%
    Aspergillin PZ is a novel isoindole-alkaloid from Aspergillus awamori. Aspergillin PZ induces conidia of P. oryzae to deform moderately.
    Aspergillin PZ
  • HY-126812
    Longestin 131774-53-3 98%
    Longestin (KS-505a) is a specific inhibitor of phosphodiesterase with antitrypanosomal activity, which is derived from Streptomyces argenteolus. Longestin is promising for research of anti-amnesia agent.
    Longestin
  • HY-126820
    Tolypomycin R 33889-22-4 98%
    Tolypomycin R is an inhibitor of poxvirus that can block the rifampin-induced virus maturation.
    Tolypomycin R
  • HY-126838
    Lavendofuseomycin 134965-82-5 98%
    Lavendofuseomycin is a macrolide pentaene antibiotic that can be utilized for antibacterial research.
    Lavendofuseomycin
  • HY-126843
    Chromozym U 112283-16-6 98%
    Chromozym U is a chromogenic agent that can be used for detection of urokinase in Shigella. Chromozym U is capable of differentiating serotypes of Shigella dysenteriae, Shigella flexneri, Shigella boydii.
    Chromozym U
  • HY-126866
    Lankacidin C 8-acetate 23812-97-7 98%
    Lankacidin C 8-acetate is an antibiotic with antibacterial activity. Lankacidin C 8-acetate, as a component of the Lankacidin group (T-2636) antibiotics, shows inhibitory effects against specific bacteria. Lankacidin C 8-acetate can generate other esterates by reacting with different acyl donors, indicating its importance in the synthesis of antibiotics.
    Lankacidin C 8-acetate
  • HY-126867
    Neohydroxyaspergillic acid 72598-34-6 98%
    Neohydroxyaspergillic acid, an antibiotic, is active against some bacteriophages.
    Neohydroxyaspergillic acid
  • HY-126869
    Pseudomonic acid D 85248-93-7 98%
    Pseudomonic acid D is a microbial inhibitor. Pseudomonic acid D potently inhibits mycoplasmas and bacterial pathogens. Pseudomonic acid D can be produced by fermentation with Pseudomonas fluorescens.
    Pseudomonic acid D
  • HY-12687R
    Tizoxanide (Standard) 173903-47-4
    Tizoxanide (Standard) is the analytical standard of Tizoxanide. This product is intended for research and analytical applications. Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has anti-HIV-1 activities and potent inhibition of both HBV and HCV replication with values EC50 of 0.46μM and 0.15 μM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-κB and the MAPK signaling pathways in LPS-treated macrophage cells.
    Tizoxanide (Standard)
  • HY-126907
    A32390A 61241-59-6 98%
    A32390A is a dopamine β-hydroxylase inhibitor and copper chelator. A32390A can inhibit the synthesis of norepinephrine, which helps lower blood pressure in DOCA hypertensive rats. A32390A can be used in research on hypertension, bacterial infections, and metabolic disorders.
    A32390A
  • HY-126924
    (Rac)-Saphenamycin 634600-55-8 98%
    (Rac)-Saphenamycin (compound CID_134184) is a gp41 inhibitor with anti-HIV-1 activity. (Rac)-Saphenamycin reveals p-p interactions with Trp571.
    (Rac)-Saphenamycin
  • HY-126929
    Trioxacarcin B 81534-36-3 98%
    Trioxacarcin B (TXN-B) is a potent cytotoxic agent and DNA-targeted inhibitor. Trioxacarcin B disrupts DNA function and induces apoptosis in cancer cells. Trioxacarcin B not only effectively inhibits the growth of various Gram-positive and Gram-negative bacteria as well as Plasmodium falciparum, but also blocks the colony formation of cancer stem cells, significantly reduces tumor volume and prolongs survival in preclinical in vivo models. The activity of Trioxacarcin B is highly dependent on its intact spiro-epoxide structure; it loses efficacy once this moiety undergoes hydrolysis, and Trioxacarcin B shows no activity against fungi, microalgae and small RNA viruses. Trioxacarcin B can be used for research on bacterial infections, malaria, and various cancers including colon cancer and melanoma.
    Trioxacarcin B
  • HY-127007
    Okilactomycin 111367-04-5 98%
    Okilactomycin is a lactone group antibiotic isolated from the culture filtrate of a strain of actinomycetes (Streptomyces species).
    Okilactomycin
  • HY-127075
    Alahopcin 82576-50-9 98%
    Alahopcin is a dipeptide antibiotic with a broad antibacterial spectrum.
    Alahopcin
  • HY-127083
    Artecanin 29431-84-3 98%
    Artecanin is a SARS-CoV-2 main protease (Mpro) inhibitor with predicted high gastrointestinal absorption and oral bioavailability, and no predicted hepatotoxicity, carcinogenicity, mutagenicity or cytotoxicity. Artecanin interacts with His41 and Cys145, the key amino acid residues in the active site of Mpro, blocks the cleavage and maturation of viral precursor proteins, and forms a stable complex with Mpro. Artecanin blocks the invasion of SARS-CoV-2. Artecanin is applicable to the research of COVID-19.
    Artecanin
  • HY-127087
    Isogarcinol 71117-97-0 98%
    Isogarcinol (Cambogin) is a potent AChE and BChE inhibitor, with IC50 values of 1.13 and 8.30 μM, respectively. Isogarcinol also shows leishmanicidal activity, with an IC50 of 0.33 μM against L. donovani.
    Isogarcinol
  • HY-127122
    Valtorcitabine dihydrochloride 359689-54-6 98%
    Valtorcitabine dihydrochloride is a prodrug of L-deoxycytidine and also is an HBV inhibitor.
    Valtorcitabine dihydrochloride
  • HY-127130
    Spicamycin 87099-85-2 98%
    Spicamycin, an adenine nucleoside antibiotic with antifungal and antitumor activities. Spicamycin is also a potent inducer of differentiation of myeloid leukemia cells. Spicamycin induces apoptosis in NB4 cells via down-regulation of Bcl-2 expression and modulation of PML protein.
    Spicamycin
  • HY-127135
    B07 1260629-43-3 98%
    B07 is a HIV inhibitor. B07 also has spermicides activity (EC50: 1.5 mg/mL).
    B07
Cat. No. Product Name / Synonyms Application Reactivity