Longestin
Longestin (KS-505a) is a specific inhibitor of phosphodiesterase with antitrypanosomal activity, which is derived from Streptomyces argenteolus. Longestin is promising for research of anti-amnesia agent.
For research use only. We do not sell to patients.
- CAS No.: 131774-53-3
- Formula: C61H88O17
- Molecular Weight:1093.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
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Biological Activity
Chemical Information
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CAS No. 131774-53-3
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Molecular Weight 1093.34
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Formula C61H88O17
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SMILES
OC[C@@]12[C@]3([H])[C@]([C@@]4([H])[C@](CC3)(OC5=CC=C(C(O)(OC6=O)CCC(OC)=O)C6=C5C4)CO)(CC[C@@]1([H])[C@]7([C@]([C@@]8([C@@]([C@]9([C@]([C@@]%10([C@@]([C@](C)([C@H](C[C@H]%10C)O[C@H]%11[C@@H]([C@H]([C@@H]([C@H](O%11)C(O)=O)O)O)OC)C(O)=O)([H])CC9)C)([H])C[C@H]8C)C)([H])CC7)C)([H])CC2)C)C
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Synonyms
KS-505a
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Structure Classification
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Initial Source
Streptomyces argenteolus A-2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ozaki T, et al. Enzymatic Formation of a Skipped Methyl-Substituted Octaprenyl Side Chain of Longestin (KS-505a): Involvement of Homo-IPP as a Common Extender Unit. Angew Chem Int Ed Engl. 2018 May 28;57(22):6629-6632. [Content Brief]
[2]. Hayashi Y, et al. Cloning of the gene cluster responsible for biosynthesis of KS-505a (longestin), a unique tetraterpenoid. Biosci Biotechnol Biochem. 2007 Dec;71(12):3072-81. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)