1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. PDE3 Isoform

PDE3

 

PDE3 Related Products (22):

Cat. No. Product Name Effect Purity
  • HY-B0809
    Theophylline
    Inhibitor 99.94%
    Theophylline (1,3-Dimethylxanthine) is a potent phosphodiesterase (PDE) inhibitor, adenosine receptor antagonist, and histone deacetylase (HDAC) activator.
  • HY-B0442A
    Vardenafil hydrochloride
    Inhibitor 99.48%
    Vardenafil hydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM.
  • HY-15485
    Zardaverine
    Inhibitor 98.73%
    Zardaverine is an orally active and selective PDE3/4 inhibitor (IC50)=0.58 uM/0.17 uM) with potent bronchodilator activity.
  • HY-B0442
    Vardenafil
    Inhibitor 99.58%
    Vardenafil is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM.
  • HY-135746
    OR-1896
    Inhibitor 99.03%
    OR-1896 is an active long-lived metabolite of Levosimendan.
  • HY-110005
    Sp-cAMPS triethylamine
    Inhibitor
    Sp-cAMPS triethylamine, a cAMP analog, is potent activator of cAMP-dependent PKA I and PKA II.
  • HY-10568
    TC-E 5005
    Inhibitor
    TC-E 5005 is a potent and selective PDE10A inhibitor with IC50 values of 7.28, 239, 779, 919, 3,100, and 3,700 nM for PDE10A, 2A, 11A, 5A, 7B and 3A, respectively.
  • HY-145924
    BAY 2666605
    Inhibitor 99.64%
    BAY 2666605 is an orally active PDE3A and PDE3B inhibitor with IC50s of 87 nM and 50 nM, respectively.
  • HY-B1639
    Enoximone
    Inhibitor 98.05%
    Enoximone is an inotropic vasodilating agent and a selective and orally active phosphodiesterase III (PDE3) inhibitor with an IC50 of 5.9 μM.
  • HY-119708
    Ensifentrine
    Inhibitor 99.47%
    Ensifentrine (RPL-554) is an inhaled first-in-class dual inhibitor of phosphodiesterase 3 (PDE3) and PDE4 with IC50s of 0.4 nM and 1479 nM, respectively.
  • HY-100530C
    Sp-cAMPS sodium salt
    Inhibitor 98.73%
    Sp-cAMPS sodium salt, a cAMP analog, is potent activator of cAMP-dependent PKA I and PKA II.
  • HY-136350
    BRD9500
    Modulator 99.60%
    BRD9500 is an orally active phosphodiesterases 3 (PDE3) inhibitor with IC50s of 10 and 27 nM for PDE3A and PDE3B, respectively.
  • HY-114672
    MBCQ
    Inhibitor 99.37%
    MBCQ is a potent and selective cGMP-specific phosphodiesterase (PDE V; PDE5) inhibitor with an IC50 of 19 nM.
  • HY-108621
    RS-25344 hydrochloride
    Inhibitor 99.50%
    RS-25344 hydrochloride is a selective cAMP-phosphodiesterase 4 (PDE 4; PDE IV) inhibitor with an IC50 of 0.28 nM in human lymphocytes.
  • HY-12887
    Piclamilast
    Inhibitor 99.09%
    Piclamilast (RP 73401) is a phosphodiesterase 4 (PDE4) inhibitor, with IC50 values of 16 nM and 2 nM in pig aorta and eosinophil soluble, respectively.
  • HY-100530B
    Sp-cAMPS
    Inhibitor
    Sp-cAMPS, a cAMP analog, is potent activator of cAMP-dependent PKA I and PKA II.
  • HY-119611A
    Thioquinapiperifil dihydrochloride
    Inhibitor 99.18%
    Thioquinapiperifil dihydrochloride (KF31327), a potent, selective and non-competitive phosphodiesterase-5 (PDE-5, IC50 of 0.074 nM) inhibitor, is used for sexual enhancement study.
  • HY-119611
    Thioquinapiperifil
    Inhibitor
    Thioquinapiperifil (KF31327 free base), a potent, selective and non-competitive phosphodiesterase-5 (PDE-5, IC50 of 0.074 nM) inhibitor, is used for sexual enhancement study.
  • HY-B0442B
    Vardenafil hydrochloride trihydrate
    Inhibitor
    Vardenafil hydrochloride trihydrate is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM.
  • HY-105349
    T-0156
    Inhibitor
    T-0156 is a potent and selective phosphodiesterase type 5 (PDE5) inhibitor.