78415-72-2
78415-72-2
Chemical Structure
Milrinone
Synonym(s): Win 47203
- CAS No.: 78415-72-2
- Formula:C12H9N3O
- Molecular Weight:211.22
IUPAC Name: 2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile
InChIKey: PZRHRDRVRGEVNW-UHFFFAOYSA-N
SMILES: CC(N1)=C(C2=CC=NC=C2)C=C(C#N)C1=O
Biological Activity: Milrinone is a PDE3 inhibitor, and also an inotrope and vasodilator.
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Milrinone | 99.86% | Milrinone is a PDE3 inhibitor, and also an inotrope and vasodilator. | ||||||||||||||||||||
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Milrinone (Standard) | ≥98% | Milrinone (Standard) is the analytical standard of Milrinone. This product is intended for research and analytical applications. Milrinone is a PDE3 inhibitor, and also an inotrope and vasodilator. | ||||||||||||||||||||
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Milrinone solution | Milrinone solution is mainly composed of Milrinone (HY-14252). Milrinone is a PDE3 inhibitor, and also an inotrope and vasodilator. | |||||||||||||||||||||
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Milrinone-d3 | Milrinone-d3 is deuterium labeled Milrinone. Milrinone is a PDE3 inhibitor, and also an inotrope and vasodilator. | |||||||||||||||||||||
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WIN-63291 | WIN-63291 is a selective and orally active phosphodiesterase (PDE) III inhibitor. WIN-63291 can be used for the research of cardiovascular disease. | |||||||||||||||||||||
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OK-1035 | OK-1035 is a selective DNA-dependent protein kinase (DNA-PK) inhibitor with an IC50 of 100 μM. | |||||||||||||||||||||
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Olprinone Hydrochloride | 99.85% | Olprinone (Loprinone) Hydrochloride is a potent and selective phosphodiesterase 3 (PDE3) inhibitor, with IC50 values of 150, 100, 0.35, and 14 μM against PDE1, PDE2, PDE3, and PDE4, respectively. Olprinone Hydrochloride exerts comprehensive protective effects including anti-inflammatory, antioxidant, and anti-apoptotic activities by elevating intracellular cAMP levels and inhibiting the NF-κB and MAPK signaling pathways. Olprinone Hydrochloride can be used in studies related to lung injury, spinal cord injury, heart failure, myocardial ischemia-reperfusion injury, and cerebral ischemic injury. | ||||||||||||||||||||
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Olprinone | 99.58% | Olprinone (Loprinone) is a potent and selective phosphodiesterase 3 (PDE3) inhibitor, with IC50 values of 150, 100, 0.35, and 14 μM against PDE1, PDE2, PDE3, and PDE4, respectively. Olprinone exerts comprehensive protective effects including anti-inflammatory, antioxidant, and anti-apoptotic activities by elevating intracellular cAMP levels and inhibiting the NF-κB and MAPK signaling pathways. Olprinone can be used in studies related to lung injury, spinal cord injury, heart failure, myocardial ischemia-reperfusion injury, and cerebral ischemic injury. | ||||||||||||||||||||
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DPN-205-734 | DPN-205-734 is an orally administered cGMP-PDE inhibitor. DPN-205-734 exhibits positive inotropic effects in various animal cardiomyocytes. DPN-205-734 reduces blood pressure and total peripheral resistance in multiple animal models, demonstrating a debulking effect. DPN-205-734 can be used in research on cardiovascular and cerebrovascular diseases such as heart failure. | |||||||||||||||||||||
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Win-62005 | Win-62005 is a cyclic AMP phosphodiesterase III (PDE III) inhibitor with Kis of 25 and 26 nM for rat heart and canine aorta, respectively. | |||||||||||||||||||||
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Win 47338 | Win 47338 (compound 14) is a control compound of inhibitors of the mitotic kinase monopolar spindle MPS1 and Aurora kinases (AurA/AurB) (Ki>100 μM). | |||||||||||||||||||||
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[4,4'-Bipyridine]-2,2'-dicarbonitrile | [4,4'-Bipyridine]-2,2'-dicarbonitrile is a metal-organic framework (MOF). | |||||||||||||||||||||
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[4,2':5',4''-Terpyridine]-4'-carbonitrile | [4,2':5',4''-Terpyridine]-4'-carbonitrile is a metal-organic framework (MOF). | |||||||||||||||||||||
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