Milrinone (Standard)
Milrinone (Standard) (Win 47203 (Standard)) is the analytical standard of Milrinone (HY-14252). This product is intended for research and analytical applications. Milrinone (Win 47203) is a selective PDE3 inhibitor with positive inotropic and vasodilatory effects. Milrinone inhibits cAMP hydrolysis and increases intracellular cAMP and PKA signaling. Milrinone reduces NF-κB, TLR4/MyD88, and NLRP3 inflammasome signaling and pro-inflammatory cytokine production, and has antioxidant and anti-apoptotic effects. Milrinone can be used in research on ischemia/reperfusion injury, sepsis, noise-induced hearing loss, acute lung injury, and Alzheimer's disease.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98%
- CAS. Nr.: 78415-72-2
- Formel: C12H9N3O
- Molecular Weight:211.22
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Anwendung
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS. Nr. 78415-72-2
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Molecular Weight 211.22
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Formel C12H9N3O
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SMILES
CC(N1)=C(C2=CC=NC=C2)C=C(C#N)C1=O
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Synonyms
Win 47203 (Standard)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Keywords
- Milrinone (Standard)
- 78415-72-2
- Win 47203 (Standard)
- Reference Standards
- Phosphodiesterase (PDE)
- PKA
- NF-κB
- Toll-like Receptor (TLR)
- MyD88
- NOD-like Receptor (NLR)
- Apoptosis
- NO Synthase
- COX
- Interleukin Related
- TNF Receptor
- Caspase
- Protein kinase A
- Nuclear factor-κB
- Nuclear factor-kappaB
- Nitric oxide synthases
- NOS
- Cyclooxygenase
- IL
- Tumor Necrosis Factor Receptor
- TNFR
- NLRP3 inflammasome
- PDE3 inhibitor
- PKA signaling
- TLR4/MyD88
- cAMP hydrolysis
- ischemia/reperfusion injury
- mBKCa channel
- mitochondrial permeability transition pore
- reactive oxygen species
- Inhibitor
- inhibitor
- inhibit