1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. PDE5 Isoform

PDE5

 

PDE5 Related Products (47):

Cat. No. Product Name Effect Purity
  • HY-15025
    Sildenafil
    Inhibitor 99.90%
    Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM.
  • HY-N0014
    Icariin
    Inhibitor 99.06%
    Icariin is a flavonol glycoside.
  • HY-15025A
    Sildenafil citrate
    Inhibitor 99.73%
    Sildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with IC50 of 5.22 nM.
  • HY-122942
    Moracin M
    Inhibitor 98.90%
    Moracin M, a phenolic component in the skin of Morus alba Linn.
  • HY-B0442A
    Vardenafil hydrochloride
    Inhibitor 99.48%
    Vardenafil hydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM.
  • HY-W011336
    PDE5-IN-7
    Inhibitor 99.59%
    PDE5-IN-7 (compound 8) is a selective phosphodiesterase 5 (PDE 5) inhibitor with an IC50 value of 5 nM, while an IC50 of 300 nM for PDE 1.
  • HY-116808B
    TPN729MA
    Inhibitor
    TPN729MA (TPN729 maleate) is a selective phosphodiesterase type 5 (PDE5) inhibitor with an IC50 value of 2.28 nM.
  • HY-116808
    TPN729
    Inhibitor
    TPN729 is a selective phosphodiesterase type 5 (PDE5) inhibitor with an IC50 value of 2.28 nM.
  • HY-18252
    Avanafil
    Inhibitor ≥98.0%
    Avanafil (TA-1790) is a potent and selective phosphodiesterase-5 (PDE-5) inhibitor with IC50 values of 5.2 nM, 630 nM, 5700 nM, 6200 nM, 12000 nM, 27000 nM, 51000 nM and 53000 nM for PDE-5, PDE-6, PDE-4, PDE-10, PDE-8, PDE-7, PDE-2 and PDE-1, respectively.
  • HY-B0442
    Vardenafil
    Inhibitor 99.58%
    Vardenafil is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM.
  • HY-109193
    Tovinontrine
    Inhibitor 99.83%
    Tovinontrine (IMR-687) is a highly potent and selective phosphodiesterase-9 (PDE9) inhibitor specifically for the treatment of sickle cell disease.
  • HY-14930A
    Mirodenafil dihydrochloride
    Inhibitor 99.79%
    Mirodenafil (SK3530) dihydrochloride is an orally active, potent, reversible, and selective phosphodiesterase 5 (PDE5) inhibitor.
  • HY-123210
    Lodenafil
    Inhibitor 99.81%
    Lodenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED).
  • HY-100933
    MY-5445
    Inhibitor 99.79%
    MY-5445 is a specific inhibitor of the cyclic GMP phosphodiesterase, phosphodiesterase type 5 (PDE5), with a Ki of 1.3 μM.
  • HY-114672
    MBCQ
    Inhibitor 99.37%
    MBCQ is a potent and selective cGMP-specific phosphodiesterase (PDE V; PDE5) inhibitor with an IC50 of 19 nM.
  • HY-114303
    CM-675
    Inhibitor 99.45%
    CM-675 is a dual phosphodiesterase 5 (PDE5) and class I histone deacetylases-selective inhibitor, with IC50 values of 114 nM and 673 nM for PDE5 and HDAC1, respectively.
  • HY-N2284
    Sophoflavescenol
    Inhibitor 98.15%
    Sophoflavescenol is a prenylated flavonol, which shows great inhibitory activity with IC50 of 0.013 μM against Phosphodiesterase 5 (PDE5), and also inhibits RLAR, HRAR, AGE, BACE1, AChE and BChE with IC50s of 0.30 µM, 0.17 µM, 17.89 µg/mL, 10.98 µM, 8.37 µM and 8.21 µM, respectively.
  • HY-90009C
    ent-Tadalafil
    Inhibitor 98.14%
    ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS).
  • HY-12887
    Piclamilast
    Inhibitor 99.09%
    Piclamilast (RP 73401) is a phosphodiesterase 4 (PDE4) inhibitor, with IC50 values of 16 nM and 2 nM in pig aorta and eosinophil soluble, respectively.
  • HY-119611A
    Thioquinapiperifil dihydrochloride
    Inhibitor 99.18%
    Thioquinapiperifil dihydrochloride (KF31327), a potent, selective and non-competitive phosphodiesterase-5 (PDE-5, IC50 of 0.074 nM) inhibitor, is used for sexual enhancement study.