1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. Autotaxin Isoform

Autotaxin

 

Autotaxin Related Products (24):

Cat. No. Product Name Effect Purity
  • HY-101772
    Ziritaxestat
    Inhibitor 99.29%
    Ziritaxestat (GLPG1690) is a first-in-class autotaxin (ATX) inhibitor, with an IC50 of 131 nM and a Ki of 15 nM.
  • HY-13344
    PF-8380
    Inhibitor 99.04%
    PF-8380 is a potent autotaxin inhibitor with an IC50 of 2.8 nM in isolated enzyme assay and 101 nM in human whole blood.
  • HY-19329
    HA130
    Inhibitor 99.43%
    HA130 is a selective autotaxin (ATX) inhibitor with an IC50 of 28 nM.
  • HY-107781
    PAT-505
    Inhibitor 99.47%
    PAT-505 is a potent, selective, noncompetitive and orally available autotaxin inhibitor, with an IC50 of 2 nM in Hep3B cells, 9.7 nM in human blood and 62 nM in mouse plasma.
  • HY-12812
    Autotaxin modulator 1
    Modulator 98.93%
    Autotaxin modulator 1 is an autotaxin (ATX) enzyme inhibitor, extracted from patent WO 2014018881 A1, Compound Example 12b.
  • HY-135053
    Autotaxin-IN-3
    Inhibitor 98.21%
    Autotaxin-IN-3 is a Autotaxin(ATX) inhibitor with an IC50 of 2.4 nM, compound 33, sourced from patent WO2018212534A1.
  • HY-133019
    ATX inhibitor 5
    Inhibitor 99.77%
    ATX inhibitor 5 is a potent and orally active autotaxin (ATX) inhibitor, with an IC50 of 15.3 nM.
  • HY-103035
    BIO-32546
    Modulator
    BIO-32546 (example 12b, S-isomer) is an autotaxin (ATX) modulator, extracted from the patent US20170158687A1.
  • HY-103267
    S32826 disodium
    Inhibitor 99.23%
    S32826 disodium is a potent autotaxin inhibitor, with an IC50 of 8.8 nM.
  • HY-13344A
    PF-8380 hydrochloride
    Inhibitor
    PF-8380 hydrochloride is a potent autotaxin inhibitor with an IC50 of 2.8 nM in isolated enzyme assay and 101 nM in human whole blood.
  • HY-135088
    Autotaxin-IN-4
    Inhibitor
    Autotaxin-IN-4 (compound 51), extracted from patent WO2018212534A1, is an Autotaxin inhibitor.
  • HY-103267A
    S32826
    Inhibitor
    S32826 is a potent autotaxin inhibitor, with an IC50 of 8.8 nM.
  • HY-146123
    ATX inhibitor 20
    Inhibitor
    ATX inhibitor 20 (compound 24) is a potent ATX (autotaxin) inhibitor, with an IC50 of 2.3 nM.
  • HY-143420
    ATX inhibitor 15
    Inhibitor
    ATX inhibitor 15 (compound 30), a indole-based carbamate derivative, is a potent autotaxin (ATX) inhibitor with an IC50 of 2.17 nM.
  • HY-144743
    ATX inhibitor 12
    Inhibitor
    ATX inhibitor 12 (compound 20) is an orally active and potent ATX (autotaxin) inhibitor, with an IC50 of 1.72 nM.
  • HY-146122
    ATX inhibitor 19
    Inhibitor
    ATX inhibitor 19 (compound 22) is a potent ATX (autotaxin) inhibitor, with an IC50 of 156 nM.
  • HY-143419
    ATX inhibitor 14
    Inhibitor
    ATX inhibitor 14 (compound 4), a indole-based carbamate derivative, is a potent autotaxin (ATX) inhibitor with an IC50 of 0.41 nM.
  • HY-123637
    Autotaxin-IN-1
    Inhibitor
    Autotaxin-IN-1 is a potent autotaxin inhibitor, which has favorable potency (IC50=2.2 nM), PK properties, and a robust PK/PD relationship.
  • HY-143581
    ATX inhibitor 8
    Inhibitor
    ATX inhibitor 8 is a Autotaxin (ATX) inhibitor extracted from patent WO2018212534A1 compound 96.
  • HY-135089
    Autotaxin-IN-5
    Inhibitor
    Autotaxin-IN-5 (compound 63), extracted from patent WO2018212534A1, is an Autotaxin inhibitor.