2402772-45-4
2402772-45-4
Chemical Structure
ATX inhibitor 5
- CAS No.: 2402772-45-4
- Formula:C22H18ClF3N6O
- Molecular Weight:474.87
IUPAC Name: (E)-N'-(4-chlorobenzylidene)-4-((3-(trifluoromethyl)phenyl)amino)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carbohydrazide
InChIKey: VHRNHTUEITYZIH-VPUKRXIYSA-N
SMILES: O=C(N/N=C/C1=CC=C(Cl)C=C1)N(C2)CCC3=C2C(NC4=CC=CC(C(F)(F)F)=C4)=NC=N3
Biological Activity: ATX inhibitor 5 is a potent and orally active autotaxin (ATX) inhibitor, with an IC50 of 15.3 nM. ATX inhibitor 5 shows anti-hepatofibrosis effects and reduces CCl4-induced hepatic fibrosis level prominently[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ATX inhibitor 5 | 98.71% | ATX inhibitor 5 is a potent and orally active autotaxin (ATX) inhibitor, with an IC50 of 15.3 nM. ATX inhibitor 5 shows anti-hepatofibrosis effects and reduces CCl4-induced hepatic fibrosis level prominently. | ||||||||||||||||||||
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