2162961-71-7

BI-2545 Chemical Structure
2162961-71-7

Chemical Structure

BI-2545

  • CAS No.: 2162961-71-7
  • Formula:C23H19F6N5O3
  • Molecular Weight:527.42

IUPAC Name: 3,5-bis(trifluoromethyl)benzyl (1R,5S,6r)-6-((1H-benzo[d][1,2,3]triazole-5-carboxamido)methyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate

InChIKey: ZDOBSAPHUUUOHX-BJWYYQGGSA-N

SMILES: O=C(N1C[C@]2([H])[C@H](CNC(C3=CC=C(NN=N4)C4=C3)=O)[C@]2([H])C1)OCC5=CC(C(F)(F)F)=CC(C(F)(F)F)=C5

Biological Activity: BI-2545, a chemical probe, is a potent autotaxin (ATX) inhibitor that significantly reduces LPA, with IC50s of 2.2 nM and 3.4 nM for human ATX and rat ATX, respectively[1].

Cat. No. Product Name Purity Description Pricing
HY-124772
BI-2545 98.85% BI-2545, a chemical probe, is a potent autotaxin (ATX) inhibitor that significantly reduces LPA, with IC50s of 2.2 nM and 3.4 nM for human ATX and rat ATX, respectively.
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