2402772-30-7

ATX inhibitor 18 Chemical Structure
2402772-30-7

Chemical Structure

ATX inhibitor 18

  • CAS No.: 2402772-30-7
  • Formula:C21H17Cl2FN6O
  • Molecular Weight:459.30

IUPAC Name: (E)-4-((3-chloro-4-fluorophenyl)amino)-N'-(4-chlorobenzylidene)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carbohydrazide

InChIKey: ARXKMGRNHJWHRP-YPXUMCKCSA-N

SMILES: O=C(N1CCC2=C(C(NC3=CC=C(C(Cl)=C3)F)=NC=N2)C1)N/N=C/C4=CC=C(C=C4)Cl

Biological Activity: ATX inhibitor 18 is a potent ATX inhibitor with an IC50 value of 24.2 nM. ATX inhibitor 18 shows antiproliferative activity and anti-fibrosis activity. ATX inhibitor 18 suppresses collagen deposition in TGF-β-mediated cardiac fibrosis[1].

Cat. No. Product Name Purity Description Pricing
HY-146205 		ATX inhibitor 18 ATX inhibitor 18 is a potent ATX inhibitor with an IC50 value of 24.2 nM. ATX inhibitor 18 shows antiproliferative activity and anti-fibrosis activity. ATX inhibitor 18 suppresses collagen deposition in TGF-β-mediated cardiac fibrosis.
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