1144035-53-9
1144035-53-9
Chemical Structure
PF-8380
- CAS No.: 1144035-53-9
- Formula:C22H21Cl2N3O5
- Molecular Weight:478.33
IUPAC Name: 3,5-dichlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate
InChIKey: JMSUDQYHPSNBSN-UHFFFAOYSA-N
SMILES: O=C(N1CCN(CC1)CCC(C2=CC(O3)=C(C=C2)NC3=O)=O)OCC4=CC(Cl)=CC(Cl)=C4
Biological Activity: PF-8380 is a potent autotaxin inhibitor with an IC50 of 2.8 nM in isolated enzyme assay and 101 nM in human whole blood.
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PF-8380 | 99.05% | PF-8380 is a potent autotaxin inhibitor with an IC50 of 2.8 nM in isolated enzyme assay and 101 nM in human whole blood. | ||||||||||||||||||||
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PF-8380 (Standard) | ≥98% | PF-8380 (Standard) is the analytical standard of PF-8380. This product is intended for research and analytical applications. PF-8380 is a potent autotaxin inhibitor with an IC50 of 2.8 nM in isolated enzyme assay and 101 nM in human whole blood. | ||||||||||||||||||||
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Keywords
