EMD-95885
Based on 1 Customer Validation
EMD-95885 is a selective NR2B-containing NMDA receptors antagonist with an IC50 of 3.9 nM. EMD-95885 does not interact with other sites on the NMDA receptor.
For research use only. We do not sell to patients.
- Purity : 98.74%
- CAS No.: 178165-43-0
- Formula: C22H23FN2O3
- Molecular Weight:382.43
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All iGluR Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
NR2B 3.9 nM (IC50) |
Chemical Information
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CAS No. 178165-43-0
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Appearance Solid
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Molecular Weight 382.43
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Formula C22H23FN2O3
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Color White to off-white
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SMILES
O=C1OC2=CC(C(CCN3CCC(CC3)CC4=CC=C(C=C4)F)=O)=CC=C2N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
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Data Sheet (264 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)