ATX inhibitor 11
Based on 1 Customer Validation
ATX inhibitor 11 (compound 13c) is a potent ATX (autotaxin) inhibitor, with an IC50 of 2.7 nM. ATX inhibitor 11 can typically alleviate the severity of fibrosis tissues and effectively reduce the deposition of fibrotic biomarker α-SMA in mice fibrosis model. ATX inhibitor 11 can be used for lung fibrosis research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.44%
- CAS. Nr.: 2485779-27-7
- Formel: C32H35N5O6
- Molecular Weight:585.65
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
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Autotaxin 2.7 ± 1 nM (IC50) |
Chemical Information
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CAS. Nr. 2485779-27-7
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Appearance Solid
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Molecular Weight 585.65
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Formel C32H35N5O6
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Color White to off-white
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SMILES
CCC1=C(N2C=C(C=C(C2=N1)C)C3=CC=C(C=C3)C(N4CCN(CC4)CCO)=O)NC(OCC5=CC6=C(OCO6)C=C5)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (170.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.7075 mL | 8.5375 mL | 17.0750 mL | 42.6876 mL |
| 5 mM | 0.3415 mL | 1.7075 mL | 3.4150 mL | 8.5375 mL | |
| 10 mM | 0.1708 mL | 0.8538 mL | 1.7075 mL | 4.2688 mL | |
| 15 mM | 0.1138 mL | 0.5692 mL | 1.1383 mL | 2.8458 mL | |
| 20 mM | 0.0854 mL | 0.4269 mL | 0.8538 mL | 2.1344 mL | |
| 25 mM | 0.0683 mL | 0.3415 mL | 0.6830 mL | 1.7075 mL | |
| 30 mM | 0.0569 mL | 0.2846 mL | 0.5692 mL | 1.4229 mL | |
| 40 mM | 0.0427 mL | 0.2134 mL | 0.4269 mL | 1.0672 mL | |
| 50 mM | 0.0342 mL | 0.1708 mL | 0.3415 mL | 0.8538 mL | |
| 60 mM | 0.0285 mL | 0.1423 mL | 0.2846 mL | 0.7115 mL | |
| 80 mM | 0.0213 mL | 0.1067 mL | 0.2134 mL | 0.5336 mL | |
| 100 mM | 0.0171 mL | 0.0854 mL | 0.1708 mL | 0.4269 mL |
ATX inhibitor 11 Related Classifications
HY-143237 Related Classifications
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