2. Search Result
Search Result
Results for "

Phosphodiesterase

" in MedChemExpress (MCE) Product Catalog:

281

Inhibitors & Agonists

1

Fluorescent Dye

5

Biochemical Assay Reagents

7

Peptides

41

Natural
Products

20

Recombinant Proteins

22

Isotope-Labeled Compounds

4

Antibodies

Species:
Tag:
Source:
Cat. No. Compare Product Name Species Source
  • HY-P77209
    SMPDL3A Protein, Mouse (HEK293, His)

    Acid sphingomyelinase-like Phosphodiesterase 3a; ASM-like Phosphodiesterase 3a; SMPDL3A; ASML3A

    		 Mouse HEK293
    SMPDL3A protein hydrolyzes nucleotide triphosphates, particularly ATP, and p-nitrophenyl-TMP. It has limited activity with nucleoside diphosphates and none with nucleoside monophosphates. SMPDL3A also catalyzes the conversion of CDP-choline to CMP and phosphocholine, and CDP-ethanolamine. However, it lacks sphingomyelin phosphodiesterase activity. SMPDL3A Protein, Mouse (HEK293, His) is the recombinant mouse-derived SMPDL3A protein, expressed by HEK293 , with C-His labeled tag. The total length of SMPDL3A Protein, Mouse (HEK293, His) is 423 a.a., with molecular weight of ~49.1 KDa.
  • HY-P74648
    PDE1C Protein, Human (sf9, His-GST)

    Phosphodiesterase; PDE1C

    		 Human Sf9 insect cells
  • HY-P71325
    SMPDL3A Protein, Human (HEK293, His)

    Acid sphingomyelinase-like Phosphodiesterase 3a; ASM-like Phosphodiesterase 3a; SMPDL3A; ASML3A

    		 Human HEK293
    SMPDL3A exhibits in vitro nucleotide phosphodiesterase activity, specifically toward ATP and p-nitrophenyl-TMP, less activity toward nucleoside diphosphates, and no activity toward nucleoside monophosphates. Notably, it showed in vitro activity with CDP-choline and CDP-ethanolamine, producing specific products. SMPDL3A Protein, Human (HEK293, His) is the recombinant human-derived SMPDL3A protein, expressed by HEK293 , with C-6*His labeled tag. The total length of SMPDL3A Protein, Human (HEK293, His) is 431 a.a., with molecular weight of ~59.0 kDa.
  • HY-P702447
    SMPD2 Protein, Human (Cell-Free, His)

    Sphingomyelin Phosphodiesterase 2; Lyso-platelet-activating factor-phospholipase C; Lyso-PAF-PLC; Neutral sphingomyelinase; N-SMase; nSMase; nSMase1

    		 Human E. coli Cell-free
    In vitro experiments have demonstrated that the sphingomyelin phosphodiesterase 2 (SMPD2) protein plays a key role in catalyzing the hydrolysis of sphingomyelin, leading to the formation of ceramide and phosphocholine. Furthermore, SMPD2 exhibits its enzymatic activity by hydrolyzing 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (hemolytic platelet-activating factor) in vivo. SMPD2 Protein, Human (Cell-Free, His) is the recombinant human-derived SMPD2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of SMPD2 Protein, Human (Cell-Free, His) is 423 a.a., with molecular weight of 49.1 kDa.
  • HY-P71591
    cGB-PDE Protein, Mouse (Myc, His)

    Pde5a; Pde5; cGMP-specific 3',5'-cyclic Phosphodiesterase; EC 3.1.4.35; cGMP-binding cGMP-specific Phosphodiesterase; CGB-PDE

    		 Mouse E. coli
    cGB-PDE protein regulates signal transduction by specifically hydrolyzing cto 5'-GMP, thereby controlling the intracellular concentration of cyclic nucleotides, particularly nitric-oxide-generated cGMP. cGB-PDE Protein, Mouse (Myc, His) is the recombinant mouse-derived cGB-PDE protein, expressed by E. coli , with N-His, C-Myc labeled tag. The total length of cGB-PDE Protein, Mouse (Myc, His) is 167 a.a., with molecular weight of ~26.1 kDa.
  • HY-P76134
    SMPD1 Protein, Mouse (sf9, His)

    Sphingomyelin Phosphodiesterase; Acid sphingomyelinase; ASMase; Smpd1; Asm

    		 Mouse Sf9 insect cells
    The SMPD1 protein converts sphingomyelin to ceramide through two enzymatic forms, one targeted to endolysosomes and the other released extracellularly. Lysosomal exocytosis becomes a significant source of the secretory form during stress responses. SMPD1 also exports cholesterol from intraendolysosomal membranes and exhibits phospholipase C activities. Its role in stress-induced apoptosis modulation is mediated through ceramide production. SMPD1 Protein, Mouse (sf9, His) is the recombinant mouse-derived SMPD1 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of SMPD1 Protein, Mouse (sf9, His) is 626 a.a., with molecular weight of ~63 KDa.
  • HY-P76710
    SMPD1 Protein, Human (sf9, His)

    Sphingomyelin Phosphodiesterase; Acid sphingomyelinase; ASMase; Smpd1; Asm

    		 Human Sf9 insect cells
    SMPD1 protein converts sphingomyelin to ceramide in lysosomes and has phospholipase C activity. SMPD1 Protein, Human (sf9, His) is the recombinant human-derived SMPD1 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of SMPD1 Protein, Human (sf9, His) is 628 a.a., with molecular weight of ~66.3 KDa.
  • HY-P70167
    ENPP-2 Protein, Human (HEK293, His)

    rHuEctonucleotide Phosphodiesterase family member 2/ENPP-2, His ; ATX; ATXFLJ26803; ATX-X; Autotaxin; autotaxin-t; EC 3.1.4.39; ectonucleotide pyrophosphatase/Phosphodiesterase 2; E-NPP 2; ENPP2; LysoPLD; NPP2; PD-IALPHA; PDNP2; PDNP2NPP2

    		 Human HEK293
    The ENPP-2 protein catalyzes the hydrolysis of lysophospholipids (especially lysophosphatidylcholine) to produce the signaling molecule lysophosphatidic acid (LPA). It also acts on sphingosine phosphocholine to produce sphingosine 1-phosphate, which affects cell movement. ENPP-2 Protein, Human (HEK293, His) is the recombinant human-derived ENPP-2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of ENPP-2 Protein, Human (HEK293, His) is 828 a.a., with molecular weight of 100-120 kDa.
  • HY-P75734
    ENPP-5 Protein, Human (HEK293, His)

    Ectonucleotide pyrophosphatase/Phosphodiesterase family member 5; NPP-5

    		 Human HEK293
    ENPP-5, exhibiting the ability to hydrolyze NAD while lacking lysopholipase D activity, does not hydrolyze nucleotide di- and triphosphates. It may contribute to neuronal cell communication through its enzymatic properties. ENPP-5 Protein, Human (HEK293, His) is the recombinant human-derived ENPP-5 protein, expressed by HEK293, with C-His labeled tag. The total length of ENPP-5 Protein, Human (HEK293, His) is 405 a.a., with molecular weight of ~81 kDa.
  • HY-P74647
    PDE2A Protein, Human (sf9, His)

    cGMP-dependent 3',5'-cyclic Phosphodiesterase; CGS-PDE; PDE2A

    		 Human Sf9 insect cells
    PDE2A is a cGMP-activated cyclic nucleotide phosphodiesterase that exhibits dual specificity for the second messengers cAMP and cGMP, key regulators in various physiological processes. PDE2A exhibits higher efficiency by covering cAMP and plays an important role in cell growth and migration. PDE2A Protein, Human (sf9, His) is the recombinant human-derived PDE2A protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of PDE2A Protein, Human (sf9, His) is 686 a.a., with molecular weight of ~80.73 kDa.
  • HY-P75963
    PDE9A Protein, Human (His)

    High affinity cGMP-specific 3',5'-cyclic Phosphodiesterase 9A; PDE9A

    		 Human E. coli
    PDE9A is a phosphodiesterase that uniquely hydrolyzes second messengers with unparalleled specificity, particularly in the regulation of natriuretic peptide-dependent signaling in the heart, which is critical for the control of cardiac hypertrophy. Its specificity rules out effects on nitric oxide-dependent signaling in the heart. PDE9A Protein, Human (His) is the recombinant human-derived PDE9A protein, expressed by E. coli , with N-His labeled tag. The total length of PDE9A Protein, Human (His) is 326 a.a., with molecular weight of ~37 kDa.
  • HY-P76902
    ENPP-7 Protein, Mouse (HEK293, His)

    Ectonucleotide pyrophosphatase/Phosphodiesterase family member 7; NPP-7; Alk-Smase

    		 Mouse HEK293
    The ENPP-7 protein acts as a choline-specific phosphodiesterase and is essential for sphingomyelin digestion, ceramide formation, and FA absorption in the gastrointestinal tract. It hydrolyzes sphingomyelin to release ceramide and phosphocholine. ENPP-7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived ENPP-7 protein, expressed by HEK293 , with C-His labeled tag. The total length of ENPP-7 Protein, Mouse (HEK293, His) is 400 a.a., with molecular weight of ~60 kDa.
  • HY-P77358
    ENPP-7 Protein, Human (HEK293, His)

    Ectonucleotide pyrophosphatase/Phosphodiesterase family member 7; NPP-7; Alk-Smase

    		 Human HEK293
    The ENPP-7 protein is a choline-specific phosphodiesterase that plays multiple roles in sphingomyelin digestion, ceramide formation, and fatty acid absorption in the gastrointestinal tract. It hydrolyzes sphingomyelin, releases ceramide and phosphocholine, and promotes the breakdown of sphingomyelin. ENPP-7 Protein, Human (HEK293, His) is the recombinant human-derived ENPP-7 protein, expressed by HEK293 , with C-His labeled tag. The total length of ENPP-7 Protein, Human (HEK293, His) is 418 a.a., with molecular weight of ~50-70 kDa.
  • HY-P701960
    PDE4D Protein, Human

    PDE4D; cAMP-specific 3'; 5'-cyclic Phosphodiesterase 4D; DPDE3; PDE43

    		 Human E. coli
    PDE4D (Phosphodiesterase 4D) protein, as a hydrolytic enzyme, degrades the second messenger cAMP, a crucial regulator in various physiological processes. Its enzymatic activity in breaking down cAMP underscores PDE4D's pivotal role in modulating cellular signaling cascades, maintaining the intricate balance of intracellular communication mediated by this critical second messenger. PDE4D Protein, Human is the recombinant human-derived PDE4D protein, expressed by E. coli , with tag free. The total length of PDE4D Protein, Human is 328 a.a., .
  • HY-P75733
    ENPP-2 Protein, Mouse (HEK293, His)

    Ectonucleotide pyrophosphatase/Phosphodiesterase family member 2; Autotaxin; LysoPLD; Npps2; Pdnp2

    		 Mouse HEK293
    ENPP-2 Protein catalyzes the hydrolysis of lysophospholipids, particularly lysophosphatidylcholine, generating the signaling molecule lysophosphatidic acid (LPA). It also acts on sphingosylphosphorylcholine, producing sphingosine-1-phosphate, influencing cell motility. ENPP-2 is involved in angiogenesis, neurite outgrowth, and tumor cell motility, showing a preference for specific lysophospholipid isomers. It plays a role in platelet activation, contributing to LPA production and cleaving sn-1 lysophospholipids. ENPP-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived ENPP-2 protein, expressed by HEK293 , with N-His, N-10*His labeled tag. The total length of ENPP-2 Protein, Mouse (HEK293, His) is 814 a.a., with molecular weight of ~100 kDa.
  • HY-P701961
    PDE4D Protein, Human (His)

    PDE4D; cAMP-specific 3'; 5'-cyclic Phosphodiesterase 4D; DPDE3; PDE43

    		 Human E. coli
    PDE4D (Phosphodiesterase 4D) protein, as a hydrolytic enzyme, degrades the second messenger cAMP, a crucial regulator in various physiological processes. Its enzymatic activity in breaking down cAMP underscores PDE4D's pivotal role in modulating cellular signaling cascades, maintaining the intricate balance of intracellular communication mediated by this critical second messenger. PDE4D Protein, Human (His) is the recombinant human-derived PDE4D protein, expressed by E. coli , with N-6*His labeled tag. The total length of PDE4D Protein, Human (His) is 328 a.a., .
  • HY-P75961
    PDE3A Protein, Human (sf9, His-GST)

    cGMP-inhibited 3',5'-cyclic Phosphodiesterase A; CGI-PDE A; PDE3A

    		 Human Sf9 insect cells
    PDE3A protein, a cyclic nucleotide phosphodiesterase, targets cAMP, cGMP, and cUMP, crucial in diverse physiological processes. In an E2/17beta-estradiol-induced pro-apoptotic pathway, E2 stabilizes the PDE3A/SLFN12 complex, leading to SLFN12 dephosphorylation and activating its pro-apoptotic ribonuclease activity. This pathway is implicated in tissues with high E2 concentrations, potentially contributing to processes like placenta remodeling. PDE3A Protein, Human (sf9, His-GST) is the recombinant human-derived PDE3A protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of PDE3A Protein, Human (sf9, His-GST) is 473 a.a., with molecular weight of ~93 kDa.
  • HY-P75962
    PDE9A Protein, Human (sf9, His-GST)

    High affinity cGMP-specific 3',5'-cyclic Phosphodiesterase 9A; PDE9A

    		 Human Sf9 insect cells
    PDE9A is a phosphodiesterase that uniquely hydrolyzes second messengers with unparalleled specificity, particularly in the regulation of natriuretic peptide-dependent signaling in the heart, which is critical for the control of cardiac hypertrophy. Its specificity rules out effects on nitric oxide-dependent signaling in the heart. PDE9A Protein, Human (sf9, His-GST) is the recombinant human-derived PDE9A protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of PDE9A Protein, Human (sf9, His-GST) is 533 a.a., with molecular weight of ~75 kDa.
  • HY-P77357
    ENPP-3 Protein, Rhesus Macaque (sf9, His)

    Ectonucleotide pyrophosphatase/Phosphodiesterase family member 3; NPP3; PD-Ibeta; PDNP3

    		 Rhesus Macaque Sf9 insect cells
    ENPP-3 is a hydrolase that metabolizes extracellular nucleotides (ATP, GTP, UTP, CTP), which is critical for immune regulation of inflammation and chronic allergic reactions. By eliminating extracellular ATP, ENPP-3 inhibits basophil and mast cell activation and suppresses the release of inflammatory cytokines. ENPP-3 Protein, Rhesus Macaque (sf9, His) is the recombinant Rhesus Macaque-derived ENPP-3 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of ENPP-3 Protein, Rhesus Macaque (sf9, His) is 829 a.a., with molecular weight of ~97.2 KDa.
  • HY-P75960
    PDE1B Protein, Human (sf9, His-GST)

    Calcium/calmodulin-dependent 3',5'-cyclic nucleotide Phosphodiesterase 1B; Cam-PDE 1B; PDE1B1; PDES1B

    		 Human Sf9 insect cells
    PDE1B protein, a cyclic nucleotide phosphodiesterase, displays dual specificity for cAMP and cGMP, essential second messengers in physiological processes. Preferring cGMP as a substrate, PDE1B fine-tunes cellular responses to cyclic nucleotide signaling. Its dual specificity underscores its regulatory role in diverse physiological pathways. PDE1B Protein, Human (sf9, His-GST) is the recombinant human-derived PDE1B protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of PDE1B Protein, Human (sf9, His-GST) is 536 a.a., with molecular weight of ~75 kDa.

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: