1. Membrane Transporter/Ion Channel
    Neuronal Signaling
    Metabolic Enzyme/Protease
  2. Calcium Channel
    Phosphodiesterase (PDE)
  3. CALP2

CALP2 

Cat. No.: HY-P1076
Handling Instructions

CALP2 is a calmodulin (CaM) antagonist ( (Kd of 7.9 µM)) with high affinity for binding to the CaM EF-hand/Ca2+-binding site. CALP2 inhibits CaM-dependent phosphodiesterase activity and increases intracellular Ca2+ concentrations. CALP2 potently inhibits of adhesion and degranulation. CALP2 is also a strong activator of alveolar macrophages.

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CALP2 Chemical Structure

CALP2 Chemical Structure

CAS No. : 261969-04-4

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Description

CALP2 is a calmodulin (CaM) antagonist ( (Kd of 7.9 µM)) with high affinity for binding to the CaM EF-hand/Ca2+-binding site. CALP2 inhibits CaM-dependent phosphodiesterase activity and increases intracellular Ca2+ concentrations. CALP2 potently inhibits of adhesion and degranulation. CALP2 is also a strong activator of alveolar macrophages[1][2][3][4].

Molecular Weight

1357.70

Formula

C₆₈H₁₀₄N₁₄O₁₃S

CAS No.

261969-04-4

Sequence

Val-Lys-Phe-Gly-Val-Gly-Phe-Lys-Val-Met-Val-Phe

Sequence Shortening

VKFGVGFKVMVF

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

CALP2CALP 2CALP-2Calcium ChannelPhosphodiesterase (PDE)Ca2+ channelsCa channelsFibronectinallergycalmodulinEF-handadhesiondegranulationalveolarmacrophagesInhibitorinhibitorinhibit

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CALP2
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HY-P1076
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