1. Membrane Transporter/Ion Channel
    Neuronal Signaling
    Metabolic Enzyme/Protease
  2. Calcium Channel
    Phosphodiesterase (PDE)
  3. CALP2 TFA

CALP2 TFA 

Cat. No.: HY-P1076A
Handling Instructions

CALP2 TFA is a calmodulin (CaM) antagonist (Kd of 7.9 µM) with high affinity for binding to the CaM EF-hand/Ca2+-binding site. CALP2 TFA inhibits CaM-dependent phosphodiesterase activity and increases intracellular Ca2+ concentrations. CALP2 TFA potently inhibits of adhesion and degranulation. CALP2 TFA is also a strong activator of alveolar macrophages.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

CALP2 TFA Chemical Structure

CALP2 TFA Chemical Structure

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Description

CALP2 TFA is a calmodulin (CaM) antagonist (Kd of 7.9 µM) with high affinity for binding to the CaM EF-hand/Ca2+-binding site. CALP2 TFA inhibits CaM-dependent phosphodiesterase activity and increases intracellular Ca2+ concentrations. CALP2 TFA potently inhibits of adhesion and degranulation. CALP2 TFA is also a strong activator of alveolar macrophages[1][2][3][4].

Molecular Weight

1471.72

Formula

C₇₀H₁₀₅F₃N₁₄O₁₅S

Sequence

Val-Lys-Phe-Gly-Val-Gly-Phe-Lys-Val-Met-Val-Phe

Sequence Shortening

VKFGVGFKVMVF

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

CALP2CALP 2CALP-2Calcium ChannelPhosphodiesterase (PDE)Ca2+ channelsCa channelsFibronectinallergycalmodulinEF-handadhesiondegranulationalveolarmacrophagesInhibitorinhibitorinhibit

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CALP2 TFA
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HY-P1076A
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