1. Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE)
  3. Thioquinapiperifil

Thioquinapiperifil (Synonyms: KF31327 free base)

Cat. No.: HY-119611
Handling Instructions

Thioquinapiperifil (KF31327 free base), a potent, selective and non-competitive phosphodiesterase-5 (PDE-5, IC50 of 0.074 nM) inhibitor, is used for sexual enhancement study.

For research use only. We do not sell to patients.

Thioquinapiperifil Chemical Structure

Thioquinapiperifil Chemical Structure

CAS No. : 220060-39-9

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Description

Thioquinapiperifil (KF31327 free base), a potent, selective and non-competitive phosphodiesterase-5 (PDE-5, IC50 of 0.074 nM) inhibitor, is used for sexual enhancement study[1][2].

IC50 & Target[2]

PDE5

0.074 nM (IC50)

PDE1

380 nM (IC50)

PDE2

670 nM (IC50)

PDE3

38 nM (IC50)

PDE4

800 nM (IC50)

In Vitro

Thioquinapiperifil can be found in dietary supplements[1].
Thioquinapiperifil (KF31327 free base) (0.1-10 μM) concentration dependently inhibits platelet aggregation. In the absence of nitroglycerin, higher concentrations 1 and 10 μM of Thioquinapiperifil (KF31327 free base) are required to inhibit platelet aggregation[2].
Thioquinapiperifil (KF31327 free base) and shows significant increase in cyclic GMP at 10 μM. After 5 min incubation, the mean cyclic GMP levels of Thioquinapiperifil (KF31327)-treated cells is 0.95±0.17 pmol/108 cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

448.58

Formula

C₂₄H₂₈N₆OS

CAS No.

220060-39-9

SMILES

S=C1NC2=CC3=C(NCC4=CC=CC=C4N5CCC(CO)CC5)N=CN=C3C=C2N1CC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

ThioquinapiperifilKF31327KF 31327KF-31327Phosphodiesterase (PDE)sexualenhancementdietarysupplementcyclicGMPInhibitorinhibitorinhibit

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Product Name:
Thioquinapiperifil
Cat. No.:
HY-119611
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