1. Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE)
  3. Thioquinapiperifil dihydrochloride

Thioquinapiperifil dihydrochloride (Synonyms: KF31327)

Cat. No.: HY-119611A
Handling Instructions

Thioquinapiperifil dihydrochloride (KF31327), a potent, selective and non-competitive phosphodiesterase-5 (PDE-5, IC50 of 0.074 nM) inhibitor, is used for sexual enhancement study.

For research use only. We do not sell to patients.

Thioquinapiperifil dihydrochloride Chemical Structure

Thioquinapiperifil dihydrochloride Chemical Structure

CAS No. : 204077-66-7

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Other Forms of Thioquinapiperifil dihydrochloride:

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Description

Thioquinapiperifil dihydrochloride (KF31327), a potent, selective and non-competitive phosphodiesterase-5 (PDE-5, IC50 of 0.074 nM) inhibitor, is used for sexual enhancement study[1][2].

IC50 & Target[2]

PDE5

0.074 nM (IC50)

PDE1

380 nM (IC50)

PDE2

670 nM (IC50)

PDE3

38 nM (IC50)

PDE4

800 nM (IC50)

In Vitro

Thioquinapiperifil can be found in dietary supplements[1].
Thioquinapiperifil dihydrochloride (KF31327) (0.1-10 μM) concentration dependently inhibits platelet aggregation. In the absence of nitroglycerin, higher concentrations 1 and 10 μM of Thioquinapiperifil dihydrochloride (KF31327) are required to inhibit platelet aggregation[2].
Thioquinapiperifil dihydrochloride (KF31327) and shows significant increase in cyclic GMP at 10 μM. After 5 min incubation, the mean cyclic GMP levels of Thioquinapiperifil dihydrochloride (KF31327)-treated cells is 0.95±0.17 pmol/108 cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

521.51

Formula

C₂₄H₃₀Cl₂N₆OS

CAS No.

204077-66-7

SMILES

[H]Cl.[H]Cl.S=C1NC2=CC3=C(NCC4=CC=CC=C4N5CCC(CO)CC5)N=CN=C3C=C2N1CC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

ThioquinapiperifilKF31327KF 31327KF-31327Phosphodiesterase (PDE)sexualenhancementdietarysupplementcyclicGMPInhibitorinhibitorinhibit

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Product Name:
Thioquinapiperifil dihydrochloride
Cat. No.:
HY-119611A
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