204077-66-7
204077-66-7
Chemical Structure
Thioquinapiperifil dihydrochloride
Synonym(s): KF31327
- CAS No.: 204077-66-7
- Formula:C24H30Cl2N6OS
- Molecular Weight:521.51
IUPAC Name: 3-ethyl-8-((2-(4-(hydroxymethyl)piperidin-1-yl)benzyl)amino)-1,3-dihydro-2H-imidazo[4,5-g]quinazoline-2-thione dihydrochloride
InChIKey: YWGNFHIWAHNADT-UHFFFAOYSA-N
SMILES: [H]Cl.[H]Cl.S=C1NC2=CC3=C(NCC4=CC=CC=C4N5CCC(CO)CC5)N=CN=C3C=C2N1CC
Biological Activity: Thioquinapiperifil dihydrochloride (KF31327), a potent, selective and non-competitive phosphodiesterase-5 (PDE-5, IC50 of 0.074 nM) inhibitor, is used for sexual enhancement study[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Thioquinapiperifil dihydrochloride | 99.22% | Thioquinapiperifil dihydrochloride (KF31327), a potent, selective and non-competitive phosphodiesterase-5 (PDE-5, IC50 of 0.074 nM) inhibitor, is used for sexual enhancement study. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.98
HY-119611Thioquinapiperifil -
Similarity Score 0.50
HY-U00422K-756 -
Similarity Score 0.47
HY-15433AQuisinostat dihydrochloride -
Similarity Score 0.47
HY-101826AER21355 hydrochloride -
Similarity Score 0.46
HY-101826ER21355 -
Similarity Score 0.46
HY-15433BQuisinostat hydrochloride -
Similarity Score 0.46
HY-103438ABIBU1361 dihydrochloride -
Similarity Score 0.46
HY-18078PQ-10 -
Similarity Score 0.46
HY-120204BI8626 -
Explore the MedChemAI to find more analogs
References
- [1]. Nahoko Uchiyama, et al. Determination of a new type of phosphodiesterase-5 inhibitor, thioquinapiperifil, in a dietary supplement promoted for sexual enhancement. Chem Pharm Bull (Tokyo). 2008 Sep;56(9):1331-4. [Content Brief]
- [2]. R Hirose, et al. KF31327, a new potent and selective inhibitor of cyclic nucleotide phosphodiesterase 5. Eur J Pharmacol. 2001 Nov 9;431(1):17-24. [Content Brief]
