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Sildenafil Mesylate

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Based on 17 publication(s) in Google Scholar

Sildenafil Mesylate is an orally active and selective phosphodiesterase type 5 (PDE5) inhibitor. Sildenafil Mesylate can be used in studies of erectile dysfunction and cancer.

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  • CAS No.: 1308285-21-3
  • Formule: C23H34N6O7S2
  • Masse moléculaire:570.68
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Sildenafil Mesylate Chemical Structure
    Sildenafil Mesylate Chemical Structure
  • Experimental Validation Results for Sildenafil Mesylate
  • Experimental Validation Results for Sildenafil Mesylate
  • Experimental Validation Results for Sildenafil Mesylate
  • Experimental Validation Results for Sildenafil Mesylate
  • Experimental Validation Results for Sildenafil Mesylate
CAS No.: 1308285-21-3
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  • Sildenafil Mesylate Chemical Structure
    Sildenafil Mesylate Chemical Structure
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    Sildenafil Mesylate purchased from MedChemExpress. Usage Cited in: Nature. 2025 Sep;645(8079):244-253. [Abstract]

    Customer Validation
     The mean velocities of immature BMDCs in 3D collagen gel treated with vehicle, 30 μM Sildenafil or sildenafil plus 10 μM ODQ. From left to right, n = 98, 79, 126 cells.

  • 1/16

    Sildenafil Mesylate purchased from MedChemExpress. Usage Cited in: Nature. 2025 Sep;645(8079):244-253. [Abstract]

    Customer Validation
     Tumour growth and survival curves of MC38-Pde5−/− tumour-bearing mice treated with vehicle or Sildenafil (20 μg/g).

  • 1/16

    Sildenafil Mesylate purchased from MedChemExpress. Usage Cited in: Physiol Rep. 2023 Jan;11(1):e15549. [Abstract]

    Customer Validation
     The index of cell proliferation in the lungs is significantly reduced in hypoxic mice that received CL316243, Sildenafil (50 mg/kg), or riociguat compared with hypoxic mice treated with vehicle.

  • 1/16

    Sildenafil Mesylate purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2022 Jun 20;23(12):6860. [Abstract]

    Customer Validation
     P62 mRNA levels in NHF upon Sildenafil treatment (100 μM, 6 h) in presence or absence of ConA (2.5 nM, 2 h).

  • 1/16

    Sildenafil Mesylate purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2022 Jun 20;23(12):6860. [Abstract]

    Customer Validation
     Analysis of the autophagic flux in NHF upon treatment with Sildenafil (100 μM, 24 h) in presence or absence of ConA (2.5 nM; 2 h).

  • Sildenafil Mesylate