1. Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE)

AMG 579 

Cat. No.: HY-12913
Handling Instructions

AMG 579 is a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A) with an IC50 of 0.1 nM.

For research use only. We do not sell to patients.

AMG 579 Chemical Structure

AMG 579 Chemical Structure

CAS No. : 1227067-61-9

Size Stock
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

AMG 579 is a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A) with an IC50 of 0.1 nM.

IC50 & Target

IC50: 0.1 nM (Phosphodiesterase 10A)[1]

Clinical Trial
Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2651 mL 11.3255 mL 22.6511 mL
5 mM 0.4530 mL 2.2651 mL 4.5302 mL
10 mM 0.2265 mL 1.1326 mL 2.2651 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

441.48

Formula

C₂₅H₂₃N₅O₃

CAS No.

1227067-61-9

SMILES

CC(N1CCC(C2=NC=CN=C2OC3=CC=C(C(C4=NC5=CC=CC=C5N4)=O)C=C3)CC1)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
AMG 579
Cat. No.:
HY-12913
Quantity:

AMG 579

Cat. No.: HY-12913