1. Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE)
  3. Ilexsaponin B2

Ilexsaponin B2 is a saponin isolated from the root of Ilex pubescens Hook. et Arn. Ilexsaponin B2 is a potent phosphodiesterase 5 (PDE5) and PDEI inhibitor with IC50 values of 48.8 μM and 477.5 μM, respectively.

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Ilexsaponin B2 Chemical Structure

Ilexsaponin B2 Chemical Structure

CAS No. : 108906-69-0

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Description

Ilexsaponin B2 is a saponin isolated from the root of Ilex pubescens Hook. et Arn. Ilexsaponin B2 is a potent phosphodiesterase 5 (PDE5) and PDEI inhibitor with IC50 values of 48.8 μM and 477.5 μM, respectively[1].

IC50 & Target[1]

PDE5

48.8 μM (IC50)

PDEI

477.5 μM (IC50)

Molecular Weight

913.10

Formula

C47H76O17

CAS No.
SMILES

OC([C@]12[C@]([C@](O)([C@@H](C)CC2)C)([H])C3=CC[C@@]([C@@]4([C@@](C(C)([C@@H](O[C@@]5([H])[C@@H]([C@H]([C@H](O)CO5)O)O[C@@]6([H])[C@@H]([C@H]([C@H](O)[C@@H](CO)O6)O)O[C@@]7([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O7)O)O)CC4)C)([H])CC8)C)([H])[C@]8(C)[C@]3(C)CC1)=O

Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Ilexsaponin B2 Related Classifications

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Ilexsaponin B2
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HY-N6256
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