PDE7-IN-2
Based on 1 Customer Validation
PDE7-IN-2 (compound 2) is a potent PDE7 (phosphodiesterase 7) inhibitor with IC50 value of 2.1 µM. PDE7-IN-2 has the potential for the research of parkinson’s disease.
For research use only. We do not sell to patients.
- Purity: ≥99.0%
- CAS No.: 107522-19-0
- Formula: C14H11ClN2O3S
- Molecular Weight:322.77
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
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PDE7A 2.1 μM (IC50) |
Chemical Information
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CAS No. 107522-19-0
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Appearance Solid
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Molecular Weight 322.77
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Formula C14H11ClN2O3S
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Color White to light yellow
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SMILES
ClC1=CC(SC2=CC=CC=C2NC(C)=O)=C(C=C1)[N+]([O-])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 30 mg/mL (92.95 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0982 mL | 15.4909 mL | 30.9818 mL | 77.4545 mL |
| 5 mM | 0.6196 mL | 3.0982 mL | 6.1964 mL | 15.4909 mL | |
| 10 mM | 0.3098 mL | 1.5491 mL | 3.0982 mL | 7.7455 mL | |
| 15 mM | 0.2065 mL | 1.0327 mL | 2.0655 mL | 5.1636 mL | |
| 20 mM | 0.1549 mL | 0.7745 mL | 1.5491 mL | 3.8727 mL | |
| 25 mM | 0.1239 mL | 0.6196 mL | 1.2393 mL | 3.0982 mL | |
| 30 mM | 0.1033 mL | 0.5164 mL | 1.0327 mL | 2.5818 mL | |
| 40 mM | 0.0775 mL | 0.3873 mL | 0.7745 mL | 1.9364 mL | |
| 50 mM | 0.0620 mL | 0.3098 mL | 0.6196 mL | 1.5491 mL | |
| 60 mM | 0.0516 mL | 0.2582 mL | 0.5164 mL | 1.2909 mL | |
| 80 mM | 0.0387 mL | 0.1936 mL | 0.3873 mL | 0.9682 mL |