1. Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE)
  3. Ro 20-1724

Ro 20-1724 (Synonyms: Ro 20-174)

Cat. No.: HY-100927
Handling Instructions

Ro 20-1724 (Ro 20-174) is a potent inhibitor of cAMP-specific phosphodiesterase (PDE4/PDE IV) with a Ki of 1930 nM. Neuroprotective effect.

For research use only. We do not sell to patients.

Ro 20-1724 Chemical Structure

Ro 20-1724 Chemical Structure

CAS No. : 29925-17-5

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Description

Ro 20-1724 (Ro 20-174) is a potent inhibitor of cAMP-specific phosphodiesterase (PDE4/PDE IV) with a Ki of 1930 nM. Neuroprotective effect[1][2].

IC50 & Target[1]

PDE4

1930 nM (Ki)

In Vivo

Ro 20-1724 (125, 250 and 500 μg/kg; i.p.; 21 days following first i.c.v. streptozotocin administration; 200-250 g adult (3-5 months old) male albino Wistar rats) significantly attenuated streptozotocin induced cognitive deficit and oxidative stress[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

278.35

Formula

C₁₅H₂₂N₂O₃

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Ro 20-1724
Cat. No.:
HY-100927
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