1. Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE)
  3. Eggmanone

Eggmanone (Synonyms: EGM1)

Cat. No.: HY-121037
Handling Instructions

Eggmanone (EGM1) is a potent and selective phosphodiesterase 4 (PDE4) antagonist with an IC50 of 72 nM for PDE4D3. Eggmanone shows approximately 40- to 50-fold selective for PDE4D3 over other PDEs. Eggmanone exerts its Hh-inhibitory effects through selective antagonism of PDE4, leading to protein kinase A activation and subsequent Hh blockade.

For research use only. We do not sell to patients.

Eggmanone Chemical Structure

Eggmanone Chemical Structure

CAS No. : 505068-32-6

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Description

Eggmanone (EGM1) is a potent and selective phosphodiesterase 4 (PDE4) antagonist with an IC50 of 72 nM for PDE4D3. Eggmanone shows approximately 40- to 50-fold selective for PDE4D3 over other PDEs. Eggmanone exerts its Hh-inhibitory effects through selective antagonism of PDE4, leading to protein kinase A activation and subsequent Hh blockade[1].

Molecular Weight

416.58

Formula

C20H20N2O2S3

CAS No.
SMILES

O=C1N(C(SCC(C2=CC=CS2)=O)=NC3=C1C4=C(CCCC4)S3)CC(C)=C

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Eggmanone
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HY-121037
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