1. Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE)
  3. MY-5445

MY-5445 

Cat. No.: HY-100933 Purity: 99.79%
Handling Instructions

MY-5445 est un inhibiteur spécifique de la phosphodiestérase de type 5 (PDE5). MY-5445 inhibe sélectivement PDE cGMP avec un Ki de 1,3 μM.

MY-5445 is a specific phosphodiesterase type 5 (PDE5) inhibitor. MY-5445 selectively inhibits cGMP PDE with a Ki of 1.3 μM.

For research use only. We do not sell to patients.

MY-5445 Chemical Structure

MY-5445 Chemical Structure

CAS No. : 78351-75-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 88 In-stock
Estimated Time of Arrival: December 31
5 mg USD 80 In-stock
Estimated Time of Arrival: December 31
10 mg USD 120 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

MY-5445 is a specific phosphodiesterase type 5 (PDE5) inhibitor[1]. MY-5445 selectively inhibits cGMP PDE with a Ki of 1.3 μM[2].

IC50 & Target[1]

PDE5

 

Molecular Weight

331.80

Formula

C₂₀H₁₄ClN₃

CAS No.

78351-75-4

SMILES

ClC1=CC(NC2=NN=C(C3=CC=CC=C3)C4=C2C=CC=C4)=CC=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (150.69 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0139 mL 15.0693 mL 30.1386 mL
5 mM 0.6028 mL 3.0139 mL 6.0277 mL
10 mM 0.3014 mL 1.5069 mL 3.0139 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.53 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.79%

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Keywords:

MY-5445MY5445MY 5445Phosphodiesterase (PDE)Inhibitorinhibitorinhibit

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Product Name:
MY-5445
Cat. No.:
HY-100933
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