1. Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE)
  3. Lodenafil

Lodenafil (Synonyms: Hydroxyhomosildenafil)

Cat. No.: HY-123210
Handling Instructions

Lodenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED), with less oral bioavailability than Lodenafil carbonate.

For research use only. We do not sell to patients.

Lodenafil Chemical Structure

Lodenafil Chemical Structure

CAS No. : 139755-85-4

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5 mg USD 150 Get quote
10 mg USD 250 Get quote
50 mg USD 850 Get quote

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Description

Lodenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED), with less oral bioavailability than Lodenafil carbonate[1].

IC50 & Target[1]

PDE5

 

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 250 mg/mL (495.44 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9818 mL 9.9088 mL 19.8177 mL
5 mM 0.3964 mL 1.9818 mL 3.9635 mL
10 mM 0.1982 mL 0.9909 mL 1.9818 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (4.12 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.12 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
Molecular Weight

504.60

Formula

C₂₃H₃₂N₆O₅S

CAS No.

139755-85-4

SMILES

O=C1C2=C(NC(C3=CC(S(=O)(N4CCN(CC4)CCO)=O)=CC=C3OCC)=N1)C(CCC)=NN2C

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Lodenafil
Cat. No.:
HY-123210
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Lodenafil

Cat. No.: HY-123210