1. Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE)
  3. Lodenafil

Lodenafil (Synonyms: Hydroxyhomosildenafil)

Cat. No.: HY-123210 Purity: 99.73%
Handling Instructions

Lodenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED).

For research use only. We do not sell to patients.

Lodenafil Chemical Structure

Lodenafil Chemical Structure

CAS No. : 139755-85-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 167 In-stock
Estimated Time of Arrival: December 31
5 mg USD 150 In-stock
Estimated Time of Arrival: December 31
10 mg USD 250 In-stock
Estimated Time of Arrival: December 31
50 mg USD 850 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Lodenafil:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

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Description

Lodenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED)[1].

IC50 & Target[1]

PDE5

 

Molecular Weight

504.60

Formula

C₂₃H₃₂N₆O₅S

CAS No.

139755-85-4

SMILES

O=C1C2=C(NC(C3=CC(S(=O)(N4CCN(CC4)CCO)=O)=CC=C3OCC)=N1)C(CCC)=NN2C

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 250 mg/mL (495.44 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9818 mL 9.9088 mL 19.8177 mL
5 mM 0.3964 mL 1.9818 mL 3.9635 mL
10 mM 0.1982 mL 0.9909 mL 1.9818 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (4.12 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.12 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.73%

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Product Name:
Lodenafil
Cat. No.:
HY-123210
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