1. Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE)
  3. TPN171

TPN171 

Cat. No.: HY-128593
Handling Instructions

TPN171 is a potent, selective and oral bioavailable inhibitor of phosphodiesterase type 5 (PDE5) with an IC50 of 0.62 nM, being developed for the treatment of pulmonary arterial hypertension (PAH).

For research use only. We do not sell to patients.

TPN171 Chemical Structure

TPN171 Chemical Structure

CAS No. : 1229018-87-4

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Description

TPN171 is a potent, selective and oral bioavailable inhibitor of phosphodiesterase type 5 (PDE5) with an IC50 of 0.62 nM, being developed for the treatment of pulmonary arterial hypertension (PAH)[1].

IC50 & Target[1]

PDE5

0.62 nM (IC50)

Molecular Weight

441.57

Formula

C₂₄H₃₅N₅O₃

CAS No.

1229018-87-4

SMILES

CCCOC1=C(C2=NC(CC)=C(CC)C(N2)=O)C=C(NC(CN3CCN(C)CC3)=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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TPN171
Cat. No.:
HY-128593
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