1. Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE)

Revizinone (Synonyms: R80122)

Cat. No.: HY-100615 Purity: 98.10%
Handling Instructions

Revizinone is a novel selective phosphodiesterase (PDE) inhibitor with IC50 values on this enzyme to 0.036 microM.

For research use only. We do not sell to patients.

Revizinone Chemical Structure

Revizinone Chemical Structure

CAS No. : 133718-29-3

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 182 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
1 mg USD 96 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
5 mg USD 180 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
10 mg USD 252 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
50 mg USD 780 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
100 mg USD 1140 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Other Forms of Revizinone:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Revizinone is a novel selective phosphodiesterase (PDE) inhibitor with IC50 values on this enzyme to 0.036 microM. target: phosphodiesterase (PDE)[3]; IC 50: 0.036 microM; [3] In vivo: The administration of Revizinone improved the haemodynamic profile with an increase in cardiac output, a decrease in systemic vascular resistance and a stable heart rate and mean arterial blood pressure. [1] With regard to reconstitution of contractility and cardiac function Revizinone (E-isomer) was 10 fold more potent than R 79595 and nearly 100 fold more potent than R 80123 (Z-isomer). [2] Revizinone significantly increased global LV function and systolic wall thickening in ischemic areas at doses greater than or equal to 0.16 mg/kg i.v. [4]

Solvent & Solubility
In Vitro: 

DMSO : ≥ 4.6 mg/mL (10.01 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1761 mL 10.8804 mL 21.7609 mL
5 mM 0.4352 mL 2.1761 mL 4.3522 mL
10 mM 0.2176 mL 1.0880 mL 2.1761 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

459.54

Formula

C₂₆H₂₉N₅O₃

CAS No.

133718-29-3

SMILES

O=C(N(C1CCCCC1)C)CO/N=C(C2=CC=CC=C2)/C3=CC4=C(N=C(NC(C5)=O)N5C4)C=C3.[(E)]

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
Revizinone
Cat. No.:
HY-100615
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Revizinone

Cat. No.: HY-100615