Enpp-1-IN-13
Enpp-1-IN-13 (Compound 1a) is an ectonucleotide pyrophosphatase/phosphodiesterase (ENPP) inhibitor with IC50 values of 1.29 μM and 20.2 μM against ENPP1 and ENPP3, respectively. Enpp-1-IN-13 shows anticancer activity.
For research use only. We do not sell to patients.
- CAS No.: 2417022-19-4
- Formula: C28H22ClN5OS
- Molecular Weight:512.03
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 1.29 μM (ENPP1), 20.2 μM (ENPP3)[1]
Enpp-1-IN-13 (Compound 1a) (100 μM) shows cytotoxic effect with inhibition of 23.0 ± 2.2%, 35.1 ± 0.8% and 30.4 ± 0.1% against HeLa, MCF-7 and 1321N1 cells, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2417022-19-4
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Molecular Weight 512.03
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Formula C28H22ClN5OS
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SMILES
S=C(NC1=CC=CC=C1)NC2=CC=CC(N3N=C(C4=CC=C(OC)C(Cl)=C4)C(C5=CC=NC=C5)=C3)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)