1. Neuronal Signaling
  2. CaMK
  3. Calmodulin antagonist-1

Calmodulin antagonist-1 

Cat. No.: HY-115745
Handling Instructions

Calmodulin antagonist-1 (W-7) is a calmodulin (CaM) antagonist. Calmodulin antagonist-1 inhibits calmodulin-activated Ca2+-phosphodiesterase (PDE) (IC50=28 μM). Calmodulin antagonist-1 also inhibits trypsin-treated Ca2+-PDE (IC50=375 μM) in a competitive fashion with respect to cyclic GMP and the Ki value is 300 μM.

For research use only. We do not sell to patients.

Calmodulin antagonist-1 Chemical Structure

Calmodulin antagonist-1 Chemical Structure

CAS No. : 78957-84-3

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Description

Calmodulin antagonist-1 (W-7) is a calmodulin (CaM) antagonist. Calmodulin antagonist-1 inhibits calmodulin-activated Ca2+-phosphodiesterase (PDE) (IC50=28 μM). Calmodulin antagonist-1 also inhibits trypsin-treated Ca2+-PDE (IC50=375 μM) in a competitive fashion with respect to cyclic GMP and the Ki value is 300 μM[1].

Molecular Weight

349.28

Formula

C₁₄H₁₈Cl₂N₂O₂S

CAS No.
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Calmodulin antagonist-1
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HY-115745
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