78957-84-3
78957-84-3
Chemical Structure
Calmodulin antagonist-1
- CAS. Nr.: 78957-84-3
- Formula:C14H18Cl2N2O2S
- Molecular Weight:349.28
IUPAC Name: N-(4-aminobutyl)-5-chloronaphthalene-1-sulfonamide hydrochloride
InChIKey: IKMXJMNRHREPOD-UHFFFAOYSA-N
SMILES: O=S(C1=C2C=CC=C(Cl)C2=CC=C1)(NCCCCN)=O.[H]Cl
Biological Activity: Calmodulin antagonist-1 (A-5) is a calmodulin (CaM) antagonist. Calmodulin antagonist-1 inhibits calmodulin-activated Ca2+-phosphodiesterase (PDE) (IC50=66 μM). Calmodulin antagonist-1 also inhibits trypsin-treated Ca2+-PDE (IC50=560 μM) in a competitive fashion with respect to cyclic GMP[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Calmodulin antagonist-1 | 99.28% | Calmodulin antagonist-1 (A-5) is a calmodulin (CaM) antagonist. Calmodulin antagonist-1 inhibits calmodulin-activated Ca2+-phosphodiesterase (PDE) (IC50=66 μM). Calmodulin antagonist-1 also inhibits trypsin-treated Ca2+-PDE (IC50=560 μM) in a competitive fashion with respect to cyclic GMP. | ||||||||||||||||||||
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