78957-84-3

Calmodulin antagonist-1 Chemical Structure
78957-84-3

Chemical Structure

Calmodulin antagonist-1

  • CAS No.: 78957-84-3
  • Formula:C14H18Cl2N2O2S
  • Molecular Weight:349.28

IUPAC Name: N-(4-aminobutyl)-5-chloronaphthalene-1-sulfonamide hydrochloride

InChIKey: IKMXJMNRHREPOD-UHFFFAOYSA-N

SMILES: O=S(C1=C2C=CC=C(Cl)C2=CC=C1)(NCCCCN)=O.[H]Cl

Biological Activity: Calmodulin antagonist-1 (A-5) is a calmodulin (CaM) antagonist. Calmodulin antagonist-1 inhibits calmodulin-activated Ca2+-phosphodiesterase (PDE) (IC50=66 μM). Calmodulin antagonist-1 also inhibits trypsin-treated Ca2+-PDE (IC50=560 μM) in a competitive fashion with respect to cyclic GMP[1].

Cat. No. Product Name Purity Description Pricing
HY-115745 		Calmodulin antagonist-1 98.0% Calmodulin antagonist-1 (A-5) is a calmodulin (CaM) antagonist. Calmodulin antagonist-1 inhibits calmodulin-activated Ca2+-phosphodiesterase (PDE) (IC50=66 μM). Calmodulin antagonist-1 also inhibits trypsin-treated Ca2+-PDE (IC50=560 μM) in a competitive fashion with respect to cyclic GMP.
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