2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. JNJ-42314415

JNJ-42314415 is a centrally active phosphodiesterase 10A (PDE10A) inhibitor, with Ki values of 35 nM and 64 nM for human recombinant PDE10A and rPDE10A, respectively.

For research use only. We do not sell to patients.

JNJ-42314415 Chemical Structure

JNJ-42314415 Chemical Structure

CAS No. : 1334165-90-0

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JNJ-42314415 Related Antibodies

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Description

JNJ-42314415 is a centrally active phosphodiesterase 10A (PDE10A) inhibitor, with Ki values of 35 nM and 64 nM for human recombinant PDE10A and rPDE10A, respectively[1].

IC50 & Target[1]

human PDE 10A

35 nM (Ki)

In Vivo

JNJ-42314415 with high dose (24.7 mg/kg) induces hypothermia[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

353.42

Formula

C19H23N5O2
CAS No.
SMILES

CC1=C(N2C(C(N3CCOCC3)=NC=C2)=N1)C4=CC=C(N=C4)CCOC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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JNJ-42314415 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JNJ-423144151334165-90-0JNJ42314415JNJ 42314415Phosphodiesterase (PDE)phosphodiesterase 10APDE10Ahypothermiaantipsychotic drugInhibitorinhibitorinhibit

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