Autotaxin-IN-6
Based on 1 Customer Validation
Autotaxin-IN-6 (compound 23) is a potent autotaxin (ATX) inhibitor with an IC50 value of 30 nM. Autotaxin-IN-6 can reduce cell migration. Autotaxin-IN-6 can be used for researching anticancer.
For research use only. We do not sell to patients.
- Purity: 99.88%
- CAS No.: 2800898-98-8
- Formula: C35H54BNO6
- Molecular Weight:595.62
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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Autotaxin 30 nM (IC50) |
Autotaxin-IN-6 (compound 23) inhibits ATX-stimulated HeLa cells and results in significantly decrease of LPA1 internalization of approximately 75%[1].
Autotaxin-IN-6 prevents LPA1 activation and its Gαi- and PI3K-dependent signaling responses[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2800898-98-8
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Appearance Solid
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Molecular Weight 595.62
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Formula C35H54BNO6
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Color White to off-white
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SMILES
O[C@@H]1[C@]2([H])[C@@](CC[C@]3([C@@]2([H])CC[C@]3([H])[C@H](C)CCC(N4CCC(CC4)OC5=CC=C(C=C5)B(O)O)=O)C)([H])[C@@]6([C@](C[C@@H](CC6)O)([H])C1)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)