1. Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE)
  3. Autotaxin modulator 1

Autotaxin modulator 1 

Cat. No.: HY-12812 Purity: 99.94%
Handling Instructions

Autotaxin modulator 1 is an autotaxin (ATX) enzyme inhibitor, extracted from patent WO 2014018881 A1, Compound Example 12b. Autotaxin modulator 1 is expected to be useful for researching demyelination due to injury or disease, as well as for researching proliferative disorders such as cancer.

For research use only. We do not sell to patients.

Autotaxin modulator 1 Chemical Structure

Autotaxin modulator 1 Chemical Structure

CAS No. : 1548743-69-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 179 In-stock
Estimated Time of Arrival: December 31
5 mg USD 150 In-stock
Estimated Time of Arrival: December 31
10 mg USD 250 In-stock
Estimated Time of Arrival: December 31
50 mg USD 750 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1250 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Autotaxin modulator 1 is an autotaxin (ATX) enzyme inhibitor, extracted from patent WO 2014018881 A1, Compound Example 12b. Autotaxin modulator 1 is expected to be useful for researching demyelination due to injury or disease, as well as for researching proliferative disorders such as cancer[1].

IC50 & Target[1]

Autotaxin

 

In Vitro

Autotaxin, a novel motility- stimulating protein, is a secreted glycoprotein widely present in biological fluids, including blood, cancer ascites, synovial, pleural and cerebrospinal fluids, originally isolated from the supernatant of melanoma cells as an autocrine motility stimulation factor[1].
Autotaxin is a member of the ectonucleotide pyrophosphatase/phosphodiesterase family of ectoenzymes (E-NPP) that hydrolyze phosphodiesterase (PDE) bonds of various nucleotides and derivatives[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

543.54

Formula

C₂₈H₃₁F₆NO₃

CAS No.

1548743-69-6

SMILES

O=C(C1CC(N2[[email protected]@H](C3=CC=C4C=CC(O[[email protected]]5CC[[email protected]@H](C(F)(F)F)CC5)=C(C(F)(F)F)C4=C3)C)CCC2C1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
References
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Keywords:

Autotaxin modulator 1Autotaxin modulator1Autotaxin modulator-1Phosphodiesterase (PDE)demyelinationlysophospholipidsubstratelysophosphatidylcholinelysophosphatidicacidInhibitorinhibitorinhibit

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Autotaxin modulator 1
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HY-12812
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