Artecanin 

Artecanin is a SARS-CoV-2 main protease (M^pro) inhibitor with predicted high gastrointestinal absorption and oral bioavailability, and no predicted hepatotoxicity, carcinogenicity, mutagenicity or cytotoxicity. Artecanin interacts with His41 and Cys145, the key amino acid residues in the active site of M^pro, blocks the cleavage and maturation of viral precursor proteins, and forms a stable complex with M^pro. Artecanin blocks the invasion of SARS-CoV-2. Artecanin is applicable to the research of COVID-19^[1].

Artecanin exhibits favorable druglikeness properties (compliant with all standard rules, high gastrointestinal absorption) and has no predicted toxicities (hepatotoxicity, carcinogenicity, mutagenicity, cytotoxicity)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

278.30

C₁₅H₁₈O₅

29431-84-3

C[C@]1(O)[C@]23[C@](O2)([C@]4([C@@](C)([C@@]3([C@@]5([C@@](CC1)(C(=C)C(=O)O5)[H])[H])[H])O4)[H])[H]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Al-Shuhaib MBS, et al. Artecanin of Laurus nobilis is a novel inhibitor of SARS-CoV-2 main protease with highly desirable druglikeness. J Biomol Struct Dyn. 2023 Apr;41(6):2355-2367.  [Content Brief]