1. Neuronal Signaling Anti-infection
  2. Cholinesterase (ChE) Parasite
  3. Isogarcinol

Isogarcinol (Cambogin) is a potent AChE and BChE inhibitor, with IC50 values of 1.13 and 8.30 μM, respectively. Isogarcinol also shows leishmanicidal activity, with an IC50 of 0.33 μM against L. donovani.

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Isogarcinol Chemical Structure

Isogarcinol Chemical Structure

CAS No. : 71117-97-0

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Description

Isogarcinol (Cambogin) is a potent AChE and BChE inhibitor, with IC50 values of 1.13 and 8.30 μM, respectively. Isogarcinol also shows leishmanicidal activity, with an IC50 of 0.33 μM against L. donovani[1].

IC50 & Target

AChE

1.13 ± 0.0 μM (IC50)

BChE

8.30 ± 0.0 μM (IC50)

Leishmania

0.33 μM (IC50)

Molecular Weight

602.80

Formula

C38H50O6

CAS No.
SMILES

O=C1[C@@]23C(OC(C)([C@H](C3)C/C=C(C)\C)C)=C(C([C@@]1(C(C)([C@@H](C2)C/C=C(C)\C)C)C/C=C(C)\C)=O)C(C4=CC(O)=C(C=C4)O)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Isogarcinol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Isogarcinol
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HY-127087
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