2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-130059
    Guanine-7-oxide 5227-68-9 98%
    Guanine-7-oxide (Guanine 7-N-oxide) is an antitumor antibiotic with anti-tumor, anti-Candida albicans activity, and can inhibit viral replication effect of herpes virus, infectious blood virus (IHNV), infectious pancreatic necrosis virus (IPNV) and so on. Guanine-7-oxide has good activity against mouse L1210 leukemia cells.
    Guanine-7-oxide
  • HY-130069
    Teicoplanin A2-5 91032-38-1 98%
    Teicoplanin A2-5 is an antibiotic active against Gram-positive aerobic and anaerobic bacteria.
    Teicoplanin A2-5
  • HY-130079
    Procaine benzylpenicillin 54-35-3 99.72%
    Procaine benzylpenicillin (Penicillin G procaine) is an antimicrobial agent. Procaine benzylpenicillin shows inhibitory activity against gram-positive bacteria and synergistic activity with Neomycin (HY-B0470). Procaine benzylpenicillin can be used in the study of bovine mastitis in animal husbandry.
    Procaine benzylpenicillin
  • HY-130187
    Sapienic acid 17004-51-2 98.10%
    Sapienic acid is a fatty acid commonly found on the skin and in mucosa. Sapienic acid has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity. Sapienic acid is active against Streptococcus sanguinis, Streptococcus mitis and Fusobacterium nucleatum with MBC values of 31.3 μg/mL, 375.0 μg/mL and 93.8 μg/mL, respectively.
    Sapienic acid
  • HY-130224
    Altromycin C 128439-48-5 98%
    Altromycin C is a pluramycin-like antibiotic with antibacterial activity. Altromycin C is related to pluramycin-type antibiotics but is structurally distinct. The biological activity of Altromycin C makes it an antibiotic complex worthy of attention.
    Altromycin C
  • HY-130282
    Ianthelliformisamine C ditrifluoroacetate 1643593-30-9 98%
    Ianthelliformisamine C ditrifluoroacetate is an antibiotic enhancer with activity against resistant Gram-negative bacteria. Ianthelliformisamine C ditrifluoroacetate has been shown to improve the efficacy of doxycycline against Pseudomonas aeruginosa. Ianthelliformisamine C ditrifluoroacetate was prepared using peptide coupling, resulting in high chemical yields of 27 to 91%. Ianthelliformisamine C ditrifluoroacetate exhibits its mechanism of action by inducing ATP efflux and causing membrane depolarization in bacterial cells.
    Ianthelliformisamine C ditrifluoroacetate
  • HY-130338
    Teicoplanin A2-3 91032-36-9 98%
    Teicoplanin A2-3 is an antibiotic active against Gram-positive aerobic and anaerobic bacteria.
    Teicoplanin A2-3
  • HY-130339
    Teicoplanin A2-4 91032-37-0 98%
    Teicoplanin A2-4 is an antibiotic active against Gram-positive aerobic and anaerobic bacteria.
    Teicoplanin A2-4
  • HY-130340
    Teicoplanin A3-1 93616-27-4 98%
    Teicoplanin A3-1 is a degradation product of teicoplanins A2-1 to 5 (Item Nos. 20187, 20188, 20189, 20192). Teicoplanins are glycopeptide antibiotics produced by A. teichomyceticus that are broadly effective against Gram-positive bacteria in vitro.
    Teicoplanin A3-1
  • HY-130349
    Emamectin B1a 121124-29-6 98%
    Emamectin B1a (L-656,748) is a semisynthetic derivative of avermectin B1a that binds to GABA receptors (Ki=17.6 nM in rat brain membranes) and enhances GABA responses. Emamectin B1a acitivates GABAA receptors α1β1γ2, α1β2γ2, and α1β3γ2 with IC50s of 57, 210, and 49.8 nM, respectively. Emamectin B1a also binds to glycine receptors, inhibiting glycine receptors with an IC50=218 nM in rat spinal cord. Emamectin B1a (1.067 ng/mL) caused 90% mortality of S. exigua larvae in foliar spray bioassays and topical application, making it more toxic than avermectin B1.
    Emamectin B1a
  • HY-130451
    Misakimycin 91776-49-7 98%
    Misakimycin is a naphthoquinone compound. Misakimycin exhibits cytotoxicity against human melanoma, breast cancer and ovarian cancer cells. Misakimycin can be found in strains of the genus Pyrenochaetopsis (strain MSX63693). Misakimycin can be used in research related to melanoma, breast cancer and ovarian cancer.
    Misakimycin
  • HY-130511
    FCE 22250 86737-06-6 98%
    FCE 22250 is a 3-azinomethylrifamycin with long-term in vivo persistence and good oral absorption. FCE 22250 shows superior efficacy against a broad antimicrobial spectrum including mycobacteria.
    FCE 22250
  • HY-130564
    Didemnin C 77327-06-1 98%
    Didemnin C is a cyclic depsipeptide. Didemnin C inhibits the proliferation of herpes simplex virus (HSV) and exhibits activity against both RNA viruses and DNA viruses. Didemnin C is cytotoxic to cancer cells. Didemnin C can be used in studies related to herpes simplex virus type 2 infection and cancer.
    Didemnin C
  • HY-130570
    β-Gal-NONOate 357192-77-9 98%
    Beta-gal-nonoate is a β-galactosidase dependent nitric oxide (NO) donor that releases NO once activated by β-galactosidase. β-Gal-NONOate has bactericidal activity and can be used as a bactericide .
    β-Gal-NONOate
  • HY-13067G
    Celastrol (GMP) 34157-83-0
    Celastrol (GMP) (Tripterine (GMP)) is Celastrol (HY-10227) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Celastrol (Tripterine;Tripterin) is a proteasome inhibitor which potently and preferentially inhibits the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM. In addition, Celastrol is also an antibiotic with potent antimicrobial activity against standard and clinical methicillin-resistant Staphylococcus aureus (MRSA) strains, inducing oxidative stress and inhibiting DNA synthesis by binding to P5CDH.
    Celastrol (GMP)
  • HY-130718
    ThrRS-IN-1 2408626-64-0 98%
    ThrRS-IN-1 (Compound 30d) is a threonyl-tRNA synthetase (ThrRS) inhibitor with an IC50 of 1.4 µM and a Kd of 1.36 µM against Salmonella enterica ThrRS (SeThrRS). ThrRS-IN-1 simultaneously targets the tRNAThr and L-threonine binding pockets of ThrRS. ThrRS-IN-1 shows potent antibacterial activities.
    ThrRS-IN-1
  • HY-130753
    JM 1397 121043-78-5 98%
    JM 1397 is an antibacterial agent that exhibits potent antibacterial activity against both methicillin-susceptible and methicillin-resistant Staphylococcus aureus with a minimum inhibitory concentration (MIC90) of 1 μg/mL..
    JM 1397
  • HY-130760
    HIV-1 integrase inhibitor 7 204268-03-1 98%
    HIV-1 integrase inhibitor 7 is a potent HIV-1 integrase inhibitor, with an IC50 of 33.3 nM.
    HIV-1 integrase inhibitor 7
  • HY-130765
    Ferbam 14484-64-1 98%
    Ferbam (Iron(III) dimethyldithiocarbamate) is a potent fungicide.
    Ferbam
  • HY-130789
    Cimigenol-3-one 31222-32-9 98%
    Cimigenol-3-one inhibits Epstein-Barr virus early antigen (EBV-EA) activation.
    Cimigenol-3-one
Cat. No. Product Name / Synonyms Application Reactivity