Didemnin C
Didemnin C is a cyclic depsipeptide. Didemnin C inhibits the proliferation of herpes simplex virus (HSV) and exhibits activity against both RNA viruses and DNA viruses. Didemnin C is cytotoxic to cancer cells. Didemnin C can be used in studies related to herpes simplex virus type 2 infection and cancer.
For research use only. We do not sell to patients.
- CAS No.: 77327-06-1
- Formula: C52H82N6O14
- Molecular Weight:1015.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| L1210 | IC50 |
0.011 μg/mL
Compound: 27
|
Cytotoxicity against mouse L1210 cells
Cytotoxicity against mouse L1210 cells
|
[PMID: 2095373] |
Chemical Information
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CAS No. 77327-06-1
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Molecular Weight 1015.24
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Formula C52H82N6O14
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SMILES
CC[C@@H]([C@@H]1[C@@H](O)CC(O[C@@H](C(C)C)C([C@H](C)C(N[C@@H](CC(C)C)C(N2CCC[C@H]2C(N(C)[C@@H](CC3=CC=C(OC)C=C3)C(O[C@H](C)[C@H](NC([C@H](N(C([C@@H](O)C)=O)C)CC(C)C)=O)C(N1)=O)=O)=O)=O)=O)=O)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1].
Rinehart KL Jr, et al. Didemnins: antiviral and antitumor depsipeptides from a caribbean tunicate. Science. 1981 May 22;212(4497):933-5.
[Content Brief]
[2].
Ali MA, et al. Didemnins as marine-derived anticancer agents: mechanistic insights and clinical potential. Med Oncol. 2025 Jan 11;42(2):43.
[Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)