1. Anti-infection
  2. HIV
    Reverse Transcriptase
  3. 4'-Ethynyl-2'-deoxyadenosine

4'-Ethynyl-2'-deoxyadenosine 

Cat. No.: HY-125810
Handling Instructions

4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity.

For research use only. We do not sell to patients.

4'-Ethynyl-2'-deoxyadenosine Chemical Structure

4'-Ethynyl-2'-deoxyadenosine Chemical Structure

CAS No. : 306305-07-7

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Description

4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity[1].

IC50 & Target

EC50: 98 nM (MT-4 cells)[1].

Molecular Weight

275.26

Formula

C₁₂H₁₃N₅O₃

CAS No.

306305-07-7

SMILES

OC[[email protected]]1(C#C)[[email protected]](C[[email protected]](N2C=NC3=C(N=CN=C32)N)O1)O

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
4'-Ethynyl-2'-deoxyadenosine
Cat. No.:
HY-125810
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