ThrRS-IN-1
ThrRS-IN-1 (Compound 30d) is a threonyl-tRNA synthetase (ThrRS) inhibitor with an IC50 of 1.4 µM and a Kd of 1.36 µM against Salmonella enterica ThrRS (SeThrRS). ThrRS-IN-1 simultaneously targets the tRNAThr and L-threonine binding pockets of ThrRS. ThrRS-IN-1 shows potent antibacterial activities.
For research use only. We do not sell to patients.
- CAS No.: 2408626-64-0
- Formula: C16H18Cl2N4O3
- Molecular Weight:385.25
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 1.4 µM (SeThrRS)[1]
Chemical Information
-
CAS No. 2408626-64-0
-
Molecular Weight 385.25
-
Formula C16H18Cl2N4O3
-
SMILES
O=C1N(C/C=C/CNC([C@@H](N)[C@H](O)C)=O)C=NC2=CC(Cl)=C(Cl)C=C21
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)